Antimicrobial peptides: a new class of antimalarial drugs?

A range of antimicrobial peptides (AMP) exhibit activity on malaria parasites, Plasmodium spp., in their blood or mosquito stages, or both. These peptides include a diverse array of both natural and synthetic molecules varying greatly in size, charge, hydrophobicity, and secondary structure features...

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Detalles Bibliográficos
Autores principales: Vale, Nuno, Aguiar, Luísa, Gomes, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271771/
https://www.ncbi.nlm.nih.gov/pubmed/25566072
http://dx.doi.org/10.3389/fphar.2014.00275
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author Vale, Nuno
Aguiar, Luísa
Gomes, Paula
author_facet Vale, Nuno
Aguiar, Luísa
Gomes, Paula
author_sort Vale, Nuno
collection PubMed
description A range of antimicrobial peptides (AMP) exhibit activity on malaria parasites, Plasmodium spp., in their blood or mosquito stages, or both. These peptides include a diverse array of both natural and synthetic molecules varying greatly in size, charge, hydrophobicity, and secondary structure features. Along with an overview of relevant literature reports regarding AMP that display antiplasmodial activity, this review makes a few considerations about those molecules as a potential new class of antimalarial drugs.
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spelling pubmed-42717712015-01-06 Antimicrobial peptides: a new class of antimalarial drugs? Vale, Nuno Aguiar, Luísa Gomes, Paula Front Pharmacol Pharmacology A range of antimicrobial peptides (AMP) exhibit activity on malaria parasites, Plasmodium spp., in their blood or mosquito stages, or both. These peptides include a diverse array of both natural and synthetic molecules varying greatly in size, charge, hydrophobicity, and secondary structure features. Along with an overview of relevant literature reports regarding AMP that display antiplasmodial activity, this review makes a few considerations about those molecules as a potential new class of antimalarial drugs. Frontiers Media S.A. 2014-12-19 /pmc/articles/PMC4271771/ /pubmed/25566072 http://dx.doi.org/10.3389/fphar.2014.00275 Text en Copyright © 2014 Vale, Aguiar and Gomes. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Vale, Nuno
Aguiar, Luísa
Gomes, Paula
Antimicrobial peptides: a new class of antimalarial drugs?
title Antimicrobial peptides: a new class of antimalarial drugs?
title_full Antimicrobial peptides: a new class of antimalarial drugs?
title_fullStr Antimicrobial peptides: a new class of antimalarial drugs?
title_full_unstemmed Antimicrobial peptides: a new class of antimalarial drugs?
title_short Antimicrobial peptides: a new class of antimalarial drugs?
title_sort antimicrobial peptides: a new class of antimalarial drugs?
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271771/
https://www.ncbi.nlm.nih.gov/pubmed/25566072
http://dx.doi.org/10.3389/fphar.2014.00275
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AT aguiarluisa antimicrobialpeptidesanewclassofantimalarialdrugs
AT gomespaula antimicrobialpeptidesanewclassofantimalarialdrugs

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