Cargando…
A robust pipeline for rapid production of versatile nanobody repertoires
Nanobodies are single domain antibodies derived from the variable regions of Camelidae atypical immunoglobulins. They show great promise as high affinity reagents for research, diagnostics and therapeutics due to their high specificity, small size (~15 kDa) and straightforward bacterial expression....
Autores principales: | Fridy, Peter C., Li, Yinyin, Keegan, Sarah, Thompson, Mary K., Nudelman, Ilona, Scheid, Johannes F., Oeffinger, Marlene, Nussenzweig, Michel C., Fenyö, David, Chait, Brian T., Rout, Michael P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272012/ https://www.ncbi.nlm.nih.gov/pubmed/25362362 http://dx.doi.org/10.1038/nmeth.3170 |
Ejemplares similares
-
Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2
por: Mast, Fred D., et al.
Publicado: (2021) -
Expanding and improving nanobody repertoires using a yeast display method: Targeting SARS-CoV-2
por: Cross, Frederick R., et al.
Publicado: (2023) -
Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus
por: Ketaren, Natalia E., et al.
Publicado: (2023) -
Llamanade: an open-source computational pipeline for robust nanobody humanization
por: Sang, Zhe, et al.
Publicado: (2021) -
Abstract 2702: Highly synergistic combinations of nanobodies that target SARS-CoV-2 reduce viral load in hACE2 transgenic mice
por: Olivier, Paul, et al.
Publicado: (2023)