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Effects of Recombinant Human Type I Pancreatic Elastase on Human Atherosclerotic Arteries

RATIONALE: At physiologic pressures, elastic fibers constrain artery diameter. Local treatment of atherosclerotic arteries with PRT-201, a recombinant type I elastase, could result in fragmentation and removal of elastin fibers and increased vessel diameter. OBJECTIVE: To investigate the use of PRT-...

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Detalles Bibliográficos
Autores principales:	Burke, Steven K., Macdonald, Karen, Moss, Emma, Bunton, David, Starcher, Barry, Wong, Marco D., Bland, Kimberly S., Franano, F. Nicholas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Journal of Cardiovascular Pharmacology 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272232/ https://www.ncbi.nlm.nih.gov/pubmed/25490419 http://dx.doi.org/10.1097/FJC.0000000000000149

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