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Rectified directional sensing in long-range cell migration

How spatial and temporal information are integrated to determine the direction of cell migration remains poorly understood. Here, by precise microfluidics emulation of dynamic chemoattractant waves, we demonstrate that, in Dictyostelium, directional movement as well as activation of small guanosine...

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Detalles Bibliográficos
Autores principales: Nakajima, Akihiko, Ishihara, Shuji, Imoto, Daisuke, Sawai, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272253/
https://www.ncbi.nlm.nih.gov/pubmed/25373620
http://dx.doi.org/10.1038/ncomms6367

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