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Dexpramipexole Is Ineffective in Two Models of ALS Related Neurodegeneration

Treatment options for people living with amyotrophic lateral sclerosis (ALS) are limited and ineffective. Recently, dexpramipexole (RPPX) was advanced into human ALS clinical trials. In the current studies, we investigated RPPX in two parallel screening systems: 1) appropriately powered, sibling-mat...

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Detalles Bibliográficos
Autores principales:	Vieira, Fernando G., LaDow, Eva, Moreno, Andy, Kidd, Joshua D., Levine, Beth, Thompson, Kenneth, Gill, Alan, Finkbeiner, Steven, Perrin, Steven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272269/ https://www.ncbi.nlm.nih.gov/pubmed/25526593 http://dx.doi.org/10.1371/journal.pone.0091608

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