Cargando…

Detection of Methylated Septin 9 in Tissue and Plasma of Colorectal Patients with Neoplasia and the Relationship to the Amount of Circulating Cell-Free DNA

BACKGROUND: Determination of methylated Septin 9 (mSEPT9) in plasma has been shown to be a sensitive and specific biomarker for colorectal cancer (CRC). However, the relationship between methylated DNA in plasma and colon tissue of the same subjects has not been reported. METHODS: Plasma and matchin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tóth, Kinga, Wasserkort, Reinhold, Sipos, Ferenc, Kalmár, Alexandra, Wichmann, Barnabás, Leiszter, Katalin, Valcz, Gábor, Juhász, Márk, Miheller, Pál, Patai, Árpád V., Tulassay, Zsolt, Molnár, Béla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272286/ https://www.ncbi.nlm.nih.gov/pubmed/25526039 http://dx.doi.org/10.1371/journal.pone.0115415

Ejemplares similares

Sporadic Colorectal Cancer Development Shows Rejuvenescence Regarding Epithelial Proliferation and Apoptosis
por: Leiszter, Katalin, et al.
Publicado: (2013)

Comprehensive DNA Methylation Analysis Reveals a Common Ten-Gene Methylation Signature in Colorectal Adenomas and Carcinomas
por: Patai, Árpád V., et al.
Publicado: (2015)

Aging related methylation influences the gene expression of key control genes in colorectal cancer and adenoma
por: Galamb, Orsolya, et al.
Publicado: (2016)

Aberrant septin 9 DNA methylation in colorectal cancer is restricted to a single CpG island
por: Wasserkort, Reinhold, et al.
Publicado: (2013)

Promoter Hypermethylation-Related Reduced Somatostatin Production Promotes Uncontrolled Cell Proliferation in Colorectal Cancer
por: Leiszter, Katalin, et al.
Publicado: (2015)

Dysplasia-Carcinoma Transition Specific Transcripts in Colonic Biopsy Samples
por: Galamb, Orsolya, et al.
Publicado: (2012)

Detection of Methylated SEPT9 in Plasma Is a Reliable Screening Method for Both Left- and Right-Sided Colon Cancers
por: Tóth, Kinga, et al.
Publicado: (2012)

Myofibroblast-Derived SFRP1 as Potential Inhibitor of Colorectal Carcinoma Field Effect
por: Valcz, Gábor, et al.
Publicado: (2014)

Peripheral Blood Based Discrimination of Ulcerative Colitis and Crohn’s Disease from Non-IBD Colitis by Genome-Wide Gene Expression Profiling
por: Sipos, Ferenc, et al.
Publicado: (2011)

Gene-expression analysis of a colorectal cancer-specific discriminatory transcript set on formalin-fixed, paraffin-embedded (FFPE) tissue samples
por: Kalmár, Alexandra, et al.
Publicado: (2015)

DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer
por: Kalmár, Alexandra, et al.
Publicado: (2015)

Gene promoter and exon DNA methylation changes in colon cancer development – mRNA expression and tumor mutation alterations
por: Molnár, Béla, et al.
Publicado: (2018)

Potential Biomarkers of Colorectal Adenoma–Dysplasia–Carcinoma Progression: mRNA Expression Profiling and In Situ Protein Detection on TMAs Reveal 15 Sequentially Upregulated and 2 Downregulated Genes
por: Galamb, Orsolya, et al.
Publicado: (2009)

Genome-wide expression profiling in colorectal cancer focusing on lncRNAs in the adenoma-carcinoma transition
por: Kalmár, Alexandra, et al.
Publicado: (2019)

Construction of a multiplex mutation hot spot PCR panel: the first step towards colorectal cancer genotyping on the GS Junior platform
por: Péterfia, Bálint, et al.
Publicado: (2017)

Applicability of Antibody and mRNA Expression Microarrays for Identifying Diagnostic and Progression Markers of Early and Late Stage Colorectal Cancer
por: Spisák, Sándor, et al.
Publicado: (2010)

Colorectal adenoma and carcinoma specific miRNA profiles in biopsy and their expression in plasma specimens
por: Nagy, Zsófia Brigitta, et al.
Publicado: (2017)

Association of Self-DNA Mediated TLR9-Related Gene, DNA Methyltransferase, and Cytokeratin Protein Expression Alterations in HT29-Cells to DNA Fragment Length and Methylation Status
por: Fűri, István, et al.
Publicado: (2013)

Inflammation, Adenoma and Cancer: Objective Classification of Colon Biopsy Specimens with Gene Expression Signature
por: Galamb, Orsolya, et al.
Publicado: (2008)

Cell Free DNA of Tumor Origin Induces a ‘Metastatic’ Expression Profile in HT-29 Cancer Cell Line
por: Fűri, István, et al.
Publicado: (2015)

Genome-Wide Screening of Genes Regulated by DNA Methylation in Colon Cancer Development
por: Spisák, Sándor, et al.
Publicado: (2012)

Perspective: bidirectional exosomal transport between cancer stem cells and their fibroblast-rich microenvironment during metastasis formation
por: Valcz, Gábor, et al.
Publicado: (2018)

Controversials of Microscopic Colitis
por: Mihaly, Emese, et al.
Publicado: (2021)

Global DNA hypomethylation of colorectal tumours detected in tissue and liquid biopsies may be related to decreased methyl-donor content
por: Szigeti, Krisztina A., et al.
Publicado: (2022)

Elevation in Peripheral Blood Circulating Tumor Cell Number Correlates with Macroscopic Progression in UICC Stage IV Colorectal Cancer Patients
por: Molnar, Bela, et al.
Publicado: (2008)

Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor
por: Galamb, O, et al.
Publicado: (2010)

Low bone mass in microscopic colitis
por: Lőrinczy, Katalin, et al.
Publicado: (2011)

Promoter Hypomethylation and Increased Expression of the Long Non-coding RNA LINC00152 Support Colorectal Carcinogenesis
por: Galamb, Orsolya, et al.
Publicado: (2020)

Small extracellular vesicle DNA-mediated horizontal gene transfer as a driving force for tumor evolution: Facts and riddles
por: Valcz, Gábor, et al.
Publicado: (2022)

Prevalence of inflammatory bowel disease among coeliac disease patients in a Hungarian coeliac centre
por: Kocsis, Dorottya, et al.
Publicado: (2015)

Folic Acid Treatment Directly Influences the Genetic and Epigenetic Regulation along with the Associated Cellular Maintenance Processes of HT-29 and SW480 Colorectal Cancer Cell Lines
por: Zsigrai, Sára, et al.
Publicado: (2022)

Relation of the IGF/IGF1R system to autophagy in colitis and colorectal cancer
por: Sipos, Ferenc, et al.
Publicado: (2017)

Diagnostic and prognostic potential of tissue and circulating long non-coding RNAs in colorectal tumors
por: Galamb, Orsolya, et al.
Publicado: (2019)

A Liquid Biopsy-Based Approach for Monitoring Treatment Response in Post-Operative Colorectal Cancer Patients
por: Barták, Barbara Kinga, et al.
Publicado: (2022)

S-Adenosylmethionine Treatment of Colorectal Cancer Cell Lines Alters DNA Methylation, DNA Repair and Tumor Progression-Related Gene Expression
por: Zsigrai, Sára, et al.
Publicado: (2020)

Neuronal-specific septin-3 binds Atg8/LC3B, accumulates and localizes to autophagosomes during induced autophagy
por: Tóth, Vilmos, et al.
Publicado: (2022)

The septins
por: Kinoshita, Makoto
Publicado: (2003)

Increased Cell Proliferation in Chronic Helicobacter pylori Positive Gastritis and Gastric Carcinoma – Correlation between Immuno-Histochemistry and Tv Image Cytometry
por: Szaleczky, Erika, et al.
Publicado: (2000)

Does Rectal Indomethacin Given for Prevention of Post-ERCP Pancreatitis Increase Bleeding After Biliary Endoscopic Sphincterotomy or Cardiovascular Mortality?: Post Hoc Analysis Using Prospective Clinical Trial Data
por: Patai, Árpád, et al.
Publicado: (2014)

En bloc release of MVB-like small extracellular vesicle clusters by colorectal carcinoma cells
por: Valcz, Gábor, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_d94eb1f4j1ugu25d8764gjv097