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COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites
Precise genome editing using engineered nucleases can significantly facilitate biological studies and disease treatment. In particular, clustered regularly interspaced short palindromic repeats (CRISPR) with CRISPR-associated (Cas) proteins are a potentially powerful tool for modifying a genome by t...
Autores principales: | Cradick, Thomas J, Qiu, Peng, Lee, Ciaran M, Fine, Eli J, Bao, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272406/ https://www.ncbi.nlm.nih.gov/pubmed/25462530 http://dx.doi.org/10.1038/mtna.2014.64 |
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