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Are We on the Path to Solve the Enigma of Resistant Hypertension: Renal Sympathetic Denervation

Renal sympathetic denervation (RSD) opens new perspectives and possibilities not only in the treatment of resistant hypertension but also of other cardiometabolic diseases. In patients with hypertension, it has been demonstrated that activity of the sympathetic nervous system correlates with grade o...

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Detalles Bibliográficos
Autores principales: Gerc, Vjekoslav, Buksa, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AVICENA, d.o.o., Sarajevo 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272464/
https://www.ncbi.nlm.nih.gov/pubmed/25568521
http://dx.doi.org/10.5455/medarh.2013.67.454-459
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author Gerc, Vjekoslav
Buksa, Marko
author_facet Gerc, Vjekoslav
Buksa, Marko
author_sort Gerc, Vjekoslav
collection PubMed
description Renal sympathetic denervation (RSD) opens new perspectives and possibilities not only in the treatment of resistant hypertension but also of other cardiometabolic diseases. In patients with hypertension, it has been demonstrated that activity of the sympathetic nervous system correlates with grade of hypertension. Decreasing sympathetic activity using RSD significantly reduces blood pressure in resistant hypertension. It is too early to say a definite opinion about appropriateness of this method in the treatment of resistant hypertension, because there are not great studies with huge number of the patients. After we get and evaluate these results through a longer span of time, only than we shall know what is the role of RSD in the treatment of resistant hypertension and other cardiometabolic conditions related to increased function of the sympathetic nervous system, such as heart failure, diabetes mellitus, obstructive sleep apnea, renal disease with microalbuminuria and macroalbuminuria.
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spelling pubmed-42724642015-01-07 Are We on the Path to Solve the Enigma of Resistant Hypertension: Renal Sympathetic Denervation Gerc, Vjekoslav Buksa, Marko Med Arch Original Paper Renal sympathetic denervation (RSD) opens new perspectives and possibilities not only in the treatment of resistant hypertension but also of other cardiometabolic diseases. In patients with hypertension, it has been demonstrated that activity of the sympathetic nervous system correlates with grade of hypertension. Decreasing sympathetic activity using RSD significantly reduces blood pressure in resistant hypertension. It is too early to say a definite opinion about appropriateness of this method in the treatment of resistant hypertension, because there are not great studies with huge number of the patients. After we get and evaluate these results through a longer span of time, only than we shall know what is the role of RSD in the treatment of resistant hypertension and other cardiometabolic conditions related to increased function of the sympathetic nervous system, such as heart failure, diabetes mellitus, obstructive sleep apnea, renal disease with microalbuminuria and macroalbuminuria. AVICENA, d.o.o., Sarajevo 2013-12-28 2013-12 /pmc/articles/PMC4272464/ /pubmed/25568521 http://dx.doi.org/10.5455/medarh.2013.67.454-459 Text en Copyright: © AVICENA http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Gerc, Vjekoslav
Buksa, Marko
Are We on the Path to Solve the Enigma of Resistant Hypertension: Renal Sympathetic Denervation
title Are We on the Path to Solve the Enigma of Resistant Hypertension: Renal Sympathetic Denervation
title_full Are We on the Path to Solve the Enigma of Resistant Hypertension: Renal Sympathetic Denervation
title_fullStr Are We on the Path to Solve the Enigma of Resistant Hypertension: Renal Sympathetic Denervation
title_full_unstemmed Are We on the Path to Solve the Enigma of Resistant Hypertension: Renal Sympathetic Denervation
title_short Are We on the Path to Solve the Enigma of Resistant Hypertension: Renal Sympathetic Denervation
title_sort are we on the path to solve the enigma of resistant hypertension: renal sympathetic denervation
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272464/
https://www.ncbi.nlm.nih.gov/pubmed/25568521
http://dx.doi.org/10.5455/medarh.2013.67.454-459
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