Diminished transmission of drug resistant HIV-1 variants with reduced replication capacity in a human transmission model

BACKGROUND: Different patterns of drug resistance are observed in treated and therapy naïve HIV-1 infected populations. Especially the NRTI-related M184I/V variants, which are among the most frequently encountered mutations in treated patients, are underrepresented in the antiretroviral naïve popula...

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Detalles Bibliográficos
Autores principales: Pingen, Marieke, Sarrami-Forooshani, Ramin, Wensing, Annemarie MJ, van Ham, Petra, Drewniak, Agata, Boucher, Charles AB, Geijtenbeek, Teunis BH, Nijhuis, Monique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272521/
https://www.ncbi.nlm.nih.gov/pubmed/25499671
http://dx.doi.org/10.1186/s12977-014-0113-9

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