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Genomic locus on chromosome 1 regulates susceptibility to spontaneous arthritis in mice deficiency of IL-1RA
BACKGROUND: To understand the role of genetic factors on chromosome 1 in the regulation of spontaneous arthritis in mice deficient in IL-1 receptor antagonist protein (IL_1RA), we previously used speed congenic breeding to transfer the QTL region from DBA/1(−/−) mice that are resistant to spontaneou...
Autores principales: | Deng, Nan, Jiao, Yan, Cao, Yanhong, Liu, Xiaoyun, Ma, Yonghui, Hasty, Karen A, Brand, David D, Stuart, John M, Gu, Weikuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272550/ https://www.ncbi.nlm.nih.gov/pubmed/25488730 http://dx.doi.org/10.1186/s12865-014-0057-9 |
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