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KRAS mutations in tumor tissue and plasma by different assays predict survival of patients with metastatic colorectal cancer
BACKGROUND: The optimal laboratory assay for detecting KRAS mutations in different biospecimens from patients with metastatic colorectal cancer (mCRC), and the clinical relevance of these gene alterations is still in question. We analyzed the prognostic–predictive relevance of KRAS status, determine...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272803/ https://www.ncbi.nlm.nih.gov/pubmed/25491325 http://dx.doi.org/10.1186/s13046-014-0104-7 |