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Genomic Reassortants of Pandemic A (H1N1) 2009 Virus and Endemic Porcine H1 and H3 Viruses in Swine in Japan

From 2010 to 2013 in Japan, we isolated 11 swine influenza viruses (SIVs) from pigs showing respiratory symptoms. Sequence and phylogenetic analyses showed that 6 H1N1 viruses originated from the pandemic (H1N1) 2009 (pdm 09) virus and the other 5 viruses were reassortants between SIVs and pdm 09 vi...

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Autores principales: KIRISAWA, Rikio, OGASAWARA, Yoshitaka, YOSHITAKE, Hayato, KODA, Asuka, FURUYA, Tokujiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272978/
https://www.ncbi.nlm.nih.gov/pubmed/25056678
http://dx.doi.org/10.1292/jvms.14-0194
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author KIRISAWA, Rikio
OGASAWARA, Yoshitaka
YOSHITAKE, Hayato
KODA, Asuka
FURUYA, Tokujiro
author_facet KIRISAWA, Rikio
OGASAWARA, Yoshitaka
YOSHITAKE, Hayato
KODA, Asuka
FURUYA, Tokujiro
author_sort KIRISAWA, Rikio
collection PubMed
description From 2010 to 2013 in Japan, we isolated 11 swine influenza viruses (SIVs) from pigs showing respiratory symptoms. Sequence and phylogenetic analyses showed that 6 H1N1 viruses originated from the pandemic (H1N1) 2009 (pdm 09) virus and the other 5 viruses were reassortants between SIVs and pdm 09 viruses, representing 4 genotypes. Two H1N2 viruses contained H1 and N2 genes originated from Japanese H1N2 SIV together with internal genes of pdm 09 viruses. Additionally, 1 H1N2 virus contained a further NP gene originating from Japanese H1N2 SIV. One H1N1 virus contained only the H1 gene originating from Japanese H1 SIV in a pdm 09 virus background. One H3N2 virus contained H3 and N2 genes originating from Japanese H3N2 SIV together with internal genes of pdm 09 virus. The results indicate that pdm 09 viruses are distributed widely in the Japanese swine population and that several reassortments with Japanese SIVs have occurred.
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spelling pubmed-42729782015-01-08 Genomic Reassortants of Pandemic A (H1N1) 2009 Virus and Endemic Porcine H1 and H3 Viruses in Swine in Japan KIRISAWA, Rikio OGASAWARA, Yoshitaka YOSHITAKE, Hayato KODA, Asuka FURUYA, Tokujiro J Vet Med Sci Virology From 2010 to 2013 in Japan, we isolated 11 swine influenza viruses (SIVs) from pigs showing respiratory symptoms. Sequence and phylogenetic analyses showed that 6 H1N1 viruses originated from the pandemic (H1N1) 2009 (pdm 09) virus and the other 5 viruses were reassortants between SIVs and pdm 09 viruses, representing 4 genotypes. Two H1N2 viruses contained H1 and N2 genes originated from Japanese H1N2 SIV together with internal genes of pdm 09 viruses. Additionally, 1 H1N2 virus contained a further NP gene originating from Japanese H1N2 SIV. One H1N1 virus contained only the H1 gene originating from Japanese H1 SIV in a pdm 09 virus background. One H3N2 virus contained H3 and N2 genes originating from Japanese H3N2 SIV together with internal genes of pdm 09 virus. The results indicate that pdm 09 viruses are distributed widely in the Japanese swine population and that several reassortments with Japanese SIVs have occurred. The Japanese Society of Veterinary Science 2014-07-24 2014-11 /pmc/articles/PMC4272978/ /pubmed/25056678 http://dx.doi.org/10.1292/jvms.14-0194 Text en ©2014 The Japanese Society of Veterinary Science http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.
spellingShingle Virology
KIRISAWA, Rikio
OGASAWARA, Yoshitaka
YOSHITAKE, Hayato
KODA, Asuka
FURUYA, Tokujiro
Genomic Reassortants of Pandemic A (H1N1) 2009 Virus and Endemic Porcine H1 and H3 Viruses in Swine in Japan
title Genomic Reassortants of Pandemic A (H1N1) 2009 Virus and Endemic Porcine H1 and H3 Viruses in Swine in Japan
title_full Genomic Reassortants of Pandemic A (H1N1) 2009 Virus and Endemic Porcine H1 and H3 Viruses in Swine in Japan
title_fullStr Genomic Reassortants of Pandemic A (H1N1) 2009 Virus and Endemic Porcine H1 and H3 Viruses in Swine in Japan
title_full_unstemmed Genomic Reassortants of Pandemic A (H1N1) 2009 Virus and Endemic Porcine H1 and H3 Viruses in Swine in Japan
title_short Genomic Reassortants of Pandemic A (H1N1) 2009 Virus and Endemic Porcine H1 and H3 Viruses in Swine in Japan
title_sort genomic reassortants of pandemic a (h1n1) 2009 virus and endemic porcine h1 and h3 viruses in swine in japan
topic Virology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272978/
https://www.ncbi.nlm.nih.gov/pubmed/25056678
http://dx.doi.org/10.1292/jvms.14-0194
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