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Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey
We aimed to estimate the cutoff value of glycated hemoglobin (HbA1c, A1c) for fasting plasma glucose (FPG) of 126 mg/dL in the Korean adult population, using the 2011 Korea National Health and Nutrition Examination Survey. A total of 5,421 participants without a history of diabetes and over 19 years...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Diabetes Association
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273035/ https://www.ncbi.nlm.nih.gov/pubmed/25541612 http://dx.doi.org/10.4093/dmj.2014.38.6.480 |
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author | Kim, Jung Min Hong, Jae Won Won, Jong Chul Noh, Jung Hyun Ko, Kyung Soo Rhee, Byoung Doo Kim, Dong-Jun |
author_facet | Kim, Jung Min Hong, Jae Won Won, Jong Chul Noh, Jung Hyun Ko, Kyung Soo Rhee, Byoung Doo Kim, Dong-Jun |
author_sort | Kim, Jung Min |
collection | PubMed |
description | We aimed to estimate the cutoff value of glycated hemoglobin (HbA1c, A1c) for fasting plasma glucose (FPG) of 126 mg/dL in the Korean adult population, using the 2011 Korea National Health and Nutrition Examination Survey. A total of 5,421 participants without a history of diabetes and over 19 years of age were included in the analysis. A point-wise area under the receiver operating characteristic curve was used to estimate the optimal A1c cutoff value. A1c threshold of 6.1% produced the highest sum of sensitivity (85.2%) and specificity (90.5%) for FPG of 126 mg/dL (area under the curve, 0.941, P<0.001). A1c of 6.5% produced a sensitivity of 67.7% and specificity of 98.0% for FPG of 126 mg/dL. Considering A1c as one of three criteria for the diagnosis of diabetes and the specificity of an A1c cutoff of 6.5%, the current diagnostic criteria of A1c≥6.5% might be acceptable in the Korean adult population. |
format | Online Article Text |
id | pubmed-4273035 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Korean Diabetes Association |
record_format | MEDLINE/PubMed |
spelling | pubmed-42730352014-12-25 Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey Kim, Jung Min Hong, Jae Won Won, Jong Chul Noh, Jung Hyun Ko, Kyung Soo Rhee, Byoung Doo Kim, Dong-Jun Diabetes Metab J Brief Report We aimed to estimate the cutoff value of glycated hemoglobin (HbA1c, A1c) for fasting plasma glucose (FPG) of 126 mg/dL in the Korean adult population, using the 2011 Korea National Health and Nutrition Examination Survey. A total of 5,421 participants without a history of diabetes and over 19 years of age were included in the analysis. A point-wise area under the receiver operating characteristic curve was used to estimate the optimal A1c cutoff value. A1c threshold of 6.1% produced the highest sum of sensitivity (85.2%) and specificity (90.5%) for FPG of 126 mg/dL (area under the curve, 0.941, P<0.001). A1c of 6.5% produced a sensitivity of 67.7% and specificity of 98.0% for FPG of 126 mg/dL. Considering A1c as one of three criteria for the diagnosis of diabetes and the specificity of an A1c cutoff of 6.5%, the current diagnostic criteria of A1c≥6.5% might be acceptable in the Korean adult population. Korean Diabetes Association 2014-12 2014-12-15 /pmc/articles/PMC4273035/ /pubmed/25541612 http://dx.doi.org/10.4093/dmj.2014.38.6.480 Text en Copyright © 2014 Korean Diabetes Association http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Brief Report Kim, Jung Min Hong, Jae Won Won, Jong Chul Noh, Jung Hyun Ko, Kyung Soo Rhee, Byoung Doo Kim, Dong-Jun Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey |
title | Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey |
title_full | Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey |
title_fullStr | Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey |
title_full_unstemmed | Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey |
title_short | Glycated Hemoglobin Value for Fasting Plasma Glucose of 126 mg/dL in Korean: The 2011 Korea National Health and Nutrition Examination Survey |
title_sort | glycated hemoglobin value for fasting plasma glucose of 126 mg/dl in korean: the 2011 korea national health and nutrition examination survey |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273035/ https://www.ncbi.nlm.nih.gov/pubmed/25541612 http://dx.doi.org/10.4093/dmj.2014.38.6.480 |
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