Excessive Labeling Technique Provides a Highly Sensitive Fluorescent Probe for Real-time Monitoring of Biodegradation of Biopolymer Pharmaceuticals in vivo

Recombinant proteins represent a large sector of the biopharma market. Determination of the main elimination pathways raises the opportunities to significantly increase their half-lives in vivo. However, evaluation of biodegradation of pharmaceutical biopolymers performed in the course of pre-clinic...

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Detalles Bibliográficos
Autores principales: Terekhov, S. S., Smirnov, I. V., Shamborant, O. G., Zenkova, M. A., Chernolovskaya, E. L., Gladkikh, D. V., Murashev, A. N., Dyachenko, I. A., Knorre, V. D., Belogurov, A. A., Ponomarenko, N. A., Deyev, S. M., Vlasov, V. V., Gabibov, A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273092/
https://www.ncbi.nlm.nih.gov/pubmed/25558395

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