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(2R,1'S,2'R)- and (2S,1'S,2'R)-3-[2-Mono(di,tri)fluoromethylcyclopropyl]alanines and their incorporation into hormaomycin analogues

Efficient and scalable syntheses of enantiomerically pure (2R,1'S,2'R)- and (2S,1'S,2'R)-3-[2-mono(di,tri)fluoromethylcyclopropyl]alanines 9a–c, as well as allo-D-threonine (4) and (2S,3R)-β-methylphenylalanine (3), using the Belokon' approach with (S)- and (R)-2-[(N-benzylp...

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Detalles Bibliográficos
Autores principales: de Meijere, Armin, Kozhushkov, Sergei I, Yufit, Dmitrii S, Grosse, Christian, Kaiser, Marcel, Raev, Vitaly A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273223/
https://www.ncbi.nlm.nih.gov/pubmed/25550751
http://dx.doi.org/10.3762/bjoc.10.302