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Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4

The pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4 strain has been synthesized using a combination of sequential glycosylations and [3 + 2] block synthetic strategy from the suitably protected monosaccharide intermediates. Thioglycosides and glycosyl trichloroacetimidate deri...

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Autor principal: Mandal, Pintu Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273275/
https://www.ncbi.nlm.nih.gov/pubmed/25550736
http://dx.doi.org/10.3762/bjoc.10.287
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author Mandal, Pintu Kumar
author_facet Mandal, Pintu Kumar
author_sort Mandal, Pintu Kumar
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description The pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4 strain has been synthesized using a combination of sequential glycosylations and [3 + 2] block synthetic strategy from the suitably protected monosaccharide intermediates. Thioglycosides and glycosyl trichloroacetimidate derivatives have been used as glycosyl donors in the glycosylations.
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spelling pubmed-42732752014-12-30 Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4 Mandal, Pintu Kumar Beilstein J Org Chem Full Research Paper The pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4 strain has been synthesized using a combination of sequential glycosylations and [3 + 2] block synthetic strategy from the suitably protected monosaccharide intermediates. Thioglycosides and glycosyl trichloroacetimidate derivatives have been used as glycosyl donors in the glycosylations. Beilstein-Institut 2014-11-20 /pmc/articles/PMC4273275/ /pubmed/25550736 http://dx.doi.org/10.3762/bjoc.10.287 Text en Copyright © 2014, Mandal https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Mandal, Pintu Kumar
Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4
title Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4
title_full Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4
title_fullStr Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4
title_full_unstemmed Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4
title_short Synthesis of the pentasaccharide repeating unit of the O-antigen of E. coli O117:K98:H4
title_sort synthesis of the pentasaccharide repeating unit of the o-antigen of e. coli o117:k98:h4
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273275/
https://www.ncbi.nlm.nih.gov/pubmed/25550736
http://dx.doi.org/10.3762/bjoc.10.287
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