Galactan synthesis in a single step via oligomerization of monosaccharides

Galactans ranging in length from one to five residues were prepared in a single step by treatment of the glycosyl donor 2,3,4-tri-O-benzoyl-β-D-galactopyranosyl fluoride with lanthanum perchlorate in the presence of an initiator alcohol. The product oligosaccharides were readily chromatographically...

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Detalles Bibliográficos
Autores principales: Dräger, Marius, Basu, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273286/
https://www.ncbi.nlm.nih.gov/pubmed/25550728
http://dx.doi.org/10.3762/bjoc.10.279
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author Dräger, Marius
Basu, Amit
author_facet Dräger, Marius
Basu, Amit
author_sort Dräger, Marius
collection PubMed
description Galactans ranging in length from one to five residues were prepared in a single step by treatment of the glycosyl donor 2,3,4-tri-O-benzoyl-β-D-galactopyranosyl fluoride with lanthanum perchlorate in the presence of an initiator alcohol. The product oligosaccharides were readily chromatographically separable. This oligomerization was used to synthesize a pentagalactan in a single step from monosaccharide building blocks in reasonable overall yields.
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spelling pubmed-42732862014-12-30 Galactan synthesis in a single step via oligomerization of monosaccharides Dräger, Marius Basu, Amit Beilstein J Org Chem Full Research Paper Galactans ranging in length from one to five residues were prepared in a single step by treatment of the glycosyl donor 2,3,4-tri-O-benzoyl-β-D-galactopyranosyl fluoride with lanthanum perchlorate in the presence of an initiator alcohol. The product oligosaccharides were readily chromatographically separable. This oligomerization was used to synthesize a pentagalactan in a single step from monosaccharide building blocks in reasonable overall yields. Beilstein-Institut 2014-11-13 /pmc/articles/PMC4273286/ /pubmed/25550728 http://dx.doi.org/10.3762/bjoc.10.279 Text en Copyright © 2014, Dräger and Basu https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Dräger, Marius
Basu, Amit
Galactan synthesis in a single step via oligomerization of monosaccharides
title Galactan synthesis in a single step via oligomerization of monosaccharides
title_full Galactan synthesis in a single step via oligomerization of monosaccharides
title_fullStr Galactan synthesis in a single step via oligomerization of monosaccharides
title_full_unstemmed Galactan synthesis in a single step via oligomerization of monosaccharides
title_short Galactan synthesis in a single step via oligomerization of monosaccharides
title_sort galactan synthesis in a single step via oligomerization of monosaccharides
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273286/
https://www.ncbi.nlm.nih.gov/pubmed/25550728
http://dx.doi.org/10.3762/bjoc.10.279
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AT basuamit galactansynthesisinasinglestepviaoligomerizationofmonosaccharides

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