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Inherently chiral calix[4]arenes via oxazoline directed ortholithiation: synthesis and probe of chiral space
The diastereoselective oxazoline-directed lithiation of calix[4]arenes is reported with diastereoselective ratios of greater than 100:1 in some instances. Notably, it has been found that the opposite diastereomer can be accessed via this approach merely through the choice of an alkyllithium reagent....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273304/ https://www.ncbi.nlm.nih.gov/pubmed/25550740 http://dx.doi.org/10.3762/bjoc.10.291 |