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A green approach to the synthesis of novel phytosphingolipidyl β-cyclodextrin designed to interact with membranes
This work reports the synthesis of a new family of mono-substituted amphiphilic cyclodextrins using a green methodology. Reactions using greener and safer catalysts with more environmentally friendly purification solvents were performed. Four unreported mono-substituted cyclodextrins bearing a phyto...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273305/ https://www.ncbi.nlm.nih.gov/pubmed/25550727 http://dx.doi.org/10.3762/bjoc.10.278 |
| Sumario: | This work reports the synthesis of a new family of mono-substituted amphiphilic cyclodextrins using a green methodology. Reactions using greener and safer catalysts with more environmentally friendly purification solvents were performed. Four unreported mono-substituted cyclodextrins bearing a phytosphingolipidyl chain and a fatty acid chain (C(10), C(12), C(14) and C(18)) were successfully obtained with a promising yield. |
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