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A green approach to the synthesis of novel phytosphingolipidyl β-cyclodextrin designed to interact with membranes

This work reports the synthesis of a new family of mono-substituted amphiphilic cyclodextrins using a green methodology. Reactions using greener and safer catalysts with more environmentally friendly purification solvents were performed. Four unreported mono-substituted cyclodextrins bearing a phyto...

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Detalles Bibliográficos
Autores principales: Miao, Yong, Djedaïni-Pilard, Florence, Bonnet, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273305/
https://www.ncbi.nlm.nih.gov/pubmed/25550727
http://dx.doi.org/10.3762/bjoc.10.278
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author Miao, Yong
Djedaïni-Pilard, Florence
Bonnet, Véronique
author_facet Miao, Yong
Djedaïni-Pilard, Florence
Bonnet, Véronique
author_sort Miao, Yong
collection PubMed
description This work reports the synthesis of a new family of mono-substituted amphiphilic cyclodextrins using a green methodology. Reactions using greener and safer catalysts with more environmentally friendly purification solvents were performed. Four unreported mono-substituted cyclodextrins bearing a phytosphingolipidyl chain and a fatty acid chain (C(10), C(12), C(14) and C(18)) were successfully obtained with a promising yield.
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spelling pubmed-42733052014-12-30 A green approach to the synthesis of novel phytosphingolipidyl β-cyclodextrin designed to interact with membranes Miao, Yong Djedaïni-Pilard, Florence Bonnet, Véronique Beilstein J Org Chem Letter This work reports the synthesis of a new family of mono-substituted amphiphilic cyclodextrins using a green methodology. Reactions using greener and safer catalysts with more environmentally friendly purification solvents were performed. Four unreported mono-substituted cyclodextrins bearing a phytosphingolipidyl chain and a fatty acid chain (C(10), C(12), C(14) and C(18)) were successfully obtained with a promising yield. Beilstein-Institut 2014-11-12 /pmc/articles/PMC4273305/ /pubmed/25550727 http://dx.doi.org/10.3762/bjoc.10.278 Text en Copyright © 2014, Miao et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Letter
Miao, Yong
Djedaïni-Pilard, Florence
Bonnet, Véronique
A green approach to the synthesis of novel phytosphingolipidyl β-cyclodextrin designed to interact with membranes
title A green approach to the synthesis of novel phytosphingolipidyl β-cyclodextrin designed to interact with membranes
title_full A green approach to the synthesis of novel phytosphingolipidyl β-cyclodextrin designed to interact with membranes
title_fullStr A green approach to the synthesis of novel phytosphingolipidyl β-cyclodextrin designed to interact with membranes
title_full_unstemmed A green approach to the synthesis of novel phytosphingolipidyl β-cyclodextrin designed to interact with membranes
title_short A green approach to the synthesis of novel phytosphingolipidyl β-cyclodextrin designed to interact with membranes
title_sort green approach to the synthesis of novel phytosphingolipidyl β-cyclodextrin designed to interact with membranes
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273305/
https://www.ncbi.nlm.nih.gov/pubmed/25550727
http://dx.doi.org/10.3762/bjoc.10.278
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