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Giant Malignant Phyllodes Tumour of Breast

The term phyllodes tumour includes lesions ranging from completely benign tumours to malignant sarcomas. Clinically phyllodes tumours are smooth, rounded, and usually painless multinodular lesions indistinguishable from fibroadenomas. Percentage of phyllodes tumour classified as malignant ranges fro...

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Detalles Bibliográficos
Autores principales: Krishnamoorthy, Ramakrishnan, Savasere, Thejas, Prabhuswamy, Vinod Kumar, Babu, Rajashekhara, Shivaswamy, Sadashivaiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273467/
https://www.ncbi.nlm.nih.gov/pubmed/25548696
http://dx.doi.org/10.1155/2014/956856
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author Krishnamoorthy, Ramakrishnan
Savasere, Thejas
Prabhuswamy, Vinod Kumar
Babu, Rajashekhara
Shivaswamy, Sadashivaiah
author_facet Krishnamoorthy, Ramakrishnan
Savasere, Thejas
Prabhuswamy, Vinod Kumar
Babu, Rajashekhara
Shivaswamy, Sadashivaiah
author_sort Krishnamoorthy, Ramakrishnan
collection PubMed
description The term phyllodes tumour includes lesions ranging from completely benign tumours to malignant sarcomas. Clinically phyllodes tumours are smooth, rounded, and usually painless multinodular lesions indistinguishable from fibroadenomas. Percentage of phyllodes tumour classified as malignant ranges from 23% to 50%. We report a case of second largest phyllodes tumour in a 35-year-old lady who presented with swelling of right breast since 6 months, initially small in size, that progressed gradually to present size. Examination revealed mass in the right breast measuring 36×32 cms with lobulated firm surface and weighing 10 kgs. Fine needle aspiration cytology was reported as borderline phyllodes; however core biopsy examination showed biphasic neoplasm with malignant stromal component. Simple mastectomy was done and specimen was sent for histopathological examination which confirmed the core biopsy report. Postoperatively the patient received chemotherapy and radiotherapy. The patient is on follow-up for a year and has not shown any evidence of metastasis or recurrence.
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spelling pubmed-42734672014-12-29 Giant Malignant Phyllodes Tumour of Breast Krishnamoorthy, Ramakrishnan Savasere, Thejas Prabhuswamy, Vinod Kumar Babu, Rajashekhara Shivaswamy, Sadashivaiah Case Rep Oncol Med Case Report The term phyllodes tumour includes lesions ranging from completely benign tumours to malignant sarcomas. Clinically phyllodes tumours are smooth, rounded, and usually painless multinodular lesions indistinguishable from fibroadenomas. Percentage of phyllodes tumour classified as malignant ranges from 23% to 50%. We report a case of second largest phyllodes tumour in a 35-year-old lady who presented with swelling of right breast since 6 months, initially small in size, that progressed gradually to present size. Examination revealed mass in the right breast measuring 36×32 cms with lobulated firm surface and weighing 10 kgs. Fine needle aspiration cytology was reported as borderline phyllodes; however core biopsy examination showed biphasic neoplasm with malignant stromal component. Simple mastectomy was done and specimen was sent for histopathological examination which confirmed the core biopsy report. Postoperatively the patient received chemotherapy and radiotherapy. The patient is on follow-up for a year and has not shown any evidence of metastasis or recurrence. Hindawi Publishing Corporation 2014 2014-12-04 /pmc/articles/PMC4273467/ /pubmed/25548696 http://dx.doi.org/10.1155/2014/956856 Text en Copyright © 2014 Ramakrishnan Krishnamoorthy et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Krishnamoorthy, Ramakrishnan
Savasere, Thejas
Prabhuswamy, Vinod Kumar
Babu, Rajashekhara
Shivaswamy, Sadashivaiah
Giant Malignant Phyllodes Tumour of Breast
title Giant Malignant Phyllodes Tumour of Breast
title_full Giant Malignant Phyllodes Tumour of Breast
title_fullStr Giant Malignant Phyllodes Tumour of Breast
title_full_unstemmed Giant Malignant Phyllodes Tumour of Breast
title_short Giant Malignant Phyllodes Tumour of Breast
title_sort giant malignant phyllodes tumour of breast
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273467/
https://www.ncbi.nlm.nih.gov/pubmed/25548696
http://dx.doi.org/10.1155/2014/956856
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