Tumor Angiogenesis Therapy Using Targeted Delivery of Paclitaxel to the Vasculature of Breast Cancer Metastases

Breast cancer aberrantly expresses tissue factor (TF) in cancer tissues and cancer vascular endothelial cells (VECs). TF plays a central role in cancer angiogenesis, growth, and metastasis and, as such, is a target for therapy and drug delivery. TF is the cognate receptor of factor VIIa (fVIIa). We...

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Detalles Bibliográficos
Autores principales: Zhu, Shijun, Kisiel, Walter, Lu, Yang J., Petersen, Lars C., Ndungu, John M., Moore, Terry W., Parker, Ernest T., Sun, Aiming, Liotta, Dennis C., El-Rayes, Bassel F., Brat, Daniel J., Snyder, James P., Shoji, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273585/
https://www.ncbi.nlm.nih.gov/pubmed/25574399
http://dx.doi.org/10.1155/2014/865732

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