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Difference in Motor Fatigue between Patients with Stroke and Patients with Multiple Sclerosis: A Pilot Study
Fatigue is often reported in stroke patients. However, it is still unclear if fatigue in stroke patients is more prominent, more frequent or more “typical” than in patients with multiple sclerosis (MS) and if the pathophysiology differs between these two populations. The purpose of this study was to...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273629/ https://www.ncbi.nlm.nih.gov/pubmed/25566183 http://dx.doi.org/10.3389/fneur.2014.00279 |
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author | Sehle, Aida Vieten, Manfred Mündermann, Annegret Dettmers, Christian |
author_facet | Sehle, Aida Vieten, Manfred Mündermann, Annegret Dettmers, Christian |
author_sort | Sehle, Aida |
collection | PubMed |
description | Fatigue is often reported in stroke patients. However, it is still unclear if fatigue in stroke patients is more prominent, more frequent or more “typical” than in patients with multiple sclerosis (MS) and if the pathophysiology differs between these two populations. The purpose of this study was to compare motor fatigue and fatigue-induced changes in kinematic gait parameters between stroke patients, MS patients, and healthy persons. Gait parameters at the beginning and end of a treadmill walking test were assessed in 10 stroke patients, 40 MS patients, and 20 healthy subjects. The recently developed Fatigue index Kliniken Schmieder (FKS) based on change of the movement’s attractor and its variability was used to measure motor fatigue. Six stroke patients had a pathological FKS. The FKS (indicating the level of motor fatigue) in stroke patients was similar compared to MS patients. Stroke patients had smaller step length, step height and greater step width, circumduction with the right and left leg, and greater sway compared to the other groups at the beginning and at the end of test. A severe walking impairment in stroke patients does not necessarily cause a pathological FKS indicating motor fatigue. Moreover, the FKS can be used as a measure of motor fatigue in stroke and MS and may also be applicable to other diseases. |
format | Online Article Text |
id | pubmed-4273629 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-42736292015-01-06 Difference in Motor Fatigue between Patients with Stroke and Patients with Multiple Sclerosis: A Pilot Study Sehle, Aida Vieten, Manfred Mündermann, Annegret Dettmers, Christian Front Neurol Neuroscience Fatigue is often reported in stroke patients. However, it is still unclear if fatigue in stroke patients is more prominent, more frequent or more “typical” than in patients with multiple sclerosis (MS) and if the pathophysiology differs between these two populations. The purpose of this study was to compare motor fatigue and fatigue-induced changes in kinematic gait parameters between stroke patients, MS patients, and healthy persons. Gait parameters at the beginning and end of a treadmill walking test were assessed in 10 stroke patients, 40 MS patients, and 20 healthy subjects. The recently developed Fatigue index Kliniken Schmieder (FKS) based on change of the movement’s attractor and its variability was used to measure motor fatigue. Six stroke patients had a pathological FKS. The FKS (indicating the level of motor fatigue) in stroke patients was similar compared to MS patients. Stroke patients had smaller step length, step height and greater step width, circumduction with the right and left leg, and greater sway compared to the other groups at the beginning and at the end of test. A severe walking impairment in stroke patients does not necessarily cause a pathological FKS indicating motor fatigue. Moreover, the FKS can be used as a measure of motor fatigue in stroke and MS and may also be applicable to other diseases. Frontiers Media S.A. 2014-12-22 /pmc/articles/PMC4273629/ /pubmed/25566183 http://dx.doi.org/10.3389/fneur.2014.00279 Text en Copyright © 2014 Sehle, Vieten, Mündermann and Dettmers. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Sehle, Aida Vieten, Manfred Mündermann, Annegret Dettmers, Christian Difference in Motor Fatigue between Patients with Stroke and Patients with Multiple Sclerosis: A Pilot Study |
title | Difference in Motor Fatigue between Patients with Stroke and Patients with Multiple Sclerosis: A Pilot Study |
title_full | Difference in Motor Fatigue between Patients with Stroke and Patients with Multiple Sclerosis: A Pilot Study |
title_fullStr | Difference in Motor Fatigue between Patients with Stroke and Patients with Multiple Sclerosis: A Pilot Study |
title_full_unstemmed | Difference in Motor Fatigue between Patients with Stroke and Patients with Multiple Sclerosis: A Pilot Study |
title_short | Difference in Motor Fatigue between Patients with Stroke and Patients with Multiple Sclerosis: A Pilot Study |
title_sort | difference in motor fatigue between patients with stroke and patients with multiple sclerosis: a pilot study |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273629/ https://www.ncbi.nlm.nih.gov/pubmed/25566183 http://dx.doi.org/10.3389/fneur.2014.00279 |
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