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Does low-level laser therapy enhance the efficacy of intravenous regional anesthesia?

BACKGROUND: The use of intravenous regional anesthesia (IVRA) is limited by pain resulting from the application of tourniquets and postoperative pain. OBJECTIVE: To assess the efficacy of low-level laser therapy added to IVRA for improving pain related to surgical fixation of distal radius fractures...

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Autores principales: Nesioonpour, Sholeh, Akhondzadeh, Reza, Mokmeli, Soheila, Moosavi, Shahnam, Mackie, Mandana, Naderan, Morteza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pulsus Group Inc 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273713/
https://www.ncbi.nlm.nih.gov/pubmed/24945286
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author Nesioonpour, Sholeh
Akhondzadeh, Reza
Mokmeli, Soheila
Moosavi, Shahnam
Mackie, Mandana
Naderan, Morteza
author_facet Nesioonpour, Sholeh
Akhondzadeh, Reza
Mokmeli, Soheila
Moosavi, Shahnam
Mackie, Mandana
Naderan, Morteza
author_sort Nesioonpour, Sholeh
collection PubMed
description BACKGROUND: The use of intravenous regional anesthesia (IVRA) is limited by pain resulting from the application of tourniquets and postoperative pain. OBJECTIVE: To assess the efficacy of low-level laser therapy added to IVRA for improving pain related to surgical fixation of distal radius fractures. METHODS: The present double-blinded, placebo-controlled, randomized clinical trial involved 48 patients who were undergoing surgical fixation of distal radius fractures. Participants were randomly assigned to either an intervention group (n=24), who received 808 nm laser irradiation as 4 J/point for 20 s over ipsilateral three nerve roots in the cervical region corresponding to C5–C8 vertebrae, and 808 nm laser irradiation as 0.1 J/cm(2) for 5 min in a tangential scanning mode over the affected extremity; or a control group (n=24), who underwent the same protocol and timing of laser probe application with the laser switched off. Both groups received the same IVRA protocol using 2% lidocaine. RESULTS: The mean visual analogue scale scores were significantly lower in the laser-assisted group than in the lidocaine-only group on all measurements during and after operation (P<0.05). The mean time to the first need for fentanyl administration during the operation was longer in the laser group (P=0.04). The total amount of fentanyl administered to patients was significantly lower in the laser-assisted group (P=0.003). The laser group needed significantly less pethidine for pain relief (P=0.001) and at a later time (P=0.002) compared with the lidocaine-only group. There was no difference between the groups in terms of mean arterial pressure and heart rate. CONCLUSION: The addition of gallium-aluminum-arsenide laser irradiation to intravenous regional anesthesia is safe, and reduces pain during and after the operation.
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spelling pubmed-42737132015-01-13 Does low-level laser therapy enhance the efficacy of intravenous regional anesthesia? Nesioonpour, Sholeh Akhondzadeh, Reza Mokmeli, Soheila Moosavi, Shahnam Mackie, Mandana Naderan, Morteza Pain Res Manag Original Article BACKGROUND: The use of intravenous regional anesthesia (IVRA) is limited by pain resulting from the application of tourniquets and postoperative pain. OBJECTIVE: To assess the efficacy of low-level laser therapy added to IVRA for improving pain related to surgical fixation of distal radius fractures. METHODS: The present double-blinded, placebo-controlled, randomized clinical trial involved 48 patients who were undergoing surgical fixation of distal radius fractures. Participants were randomly assigned to either an intervention group (n=24), who received 808 nm laser irradiation as 4 J/point for 20 s over ipsilateral three nerve roots in the cervical region corresponding to C5–C8 vertebrae, and 808 nm laser irradiation as 0.1 J/cm(2) for 5 min in a tangential scanning mode over the affected extremity; or a control group (n=24), who underwent the same protocol and timing of laser probe application with the laser switched off. Both groups received the same IVRA protocol using 2% lidocaine. RESULTS: The mean visual analogue scale scores were significantly lower in the laser-assisted group than in the lidocaine-only group on all measurements during and after operation (P<0.05). The mean time to the first need for fentanyl administration during the operation was longer in the laser group (P=0.04). The total amount of fentanyl administered to patients was significantly lower in the laser-assisted group (P=0.003). The laser group needed significantly less pethidine for pain relief (P=0.001) and at a later time (P=0.002) compared with the lidocaine-only group. There was no difference between the groups in terms of mean arterial pressure and heart rate. CONCLUSION: The addition of gallium-aluminum-arsenide laser irradiation to intravenous regional anesthesia is safe, and reduces pain during and after the operation. Pulsus Group Inc 2014 /pmc/articles/PMC4273713/ /pubmed/24945286 Text en © 2014, Pulsus Group Inc. All rights reserved This open-access article is distributed under the terms of the Creative Commons Attribution Non-Commercial License (CC BY-NC) (http://creativecommons.org/licenses/by-nc/4.0/), which permits reuse, distribution and reproduction of the article, provided that the original work is properly cited and the reuse is restricted to noncommercial purposes. For commercial reuse, contact support@pulsus.com
spellingShingle Original Article
Nesioonpour, Sholeh
Akhondzadeh, Reza
Mokmeli, Soheila
Moosavi, Shahnam
Mackie, Mandana
Naderan, Morteza
Does low-level laser therapy enhance the efficacy of intravenous regional anesthesia?
title Does low-level laser therapy enhance the efficacy of intravenous regional anesthesia?
title_full Does low-level laser therapy enhance the efficacy of intravenous regional anesthesia?
title_fullStr Does low-level laser therapy enhance the efficacy of intravenous regional anesthesia?
title_full_unstemmed Does low-level laser therapy enhance the efficacy of intravenous regional anesthesia?
title_short Does low-level laser therapy enhance the efficacy of intravenous regional anesthesia?
title_sort does low-level laser therapy enhance the efficacy of intravenous regional anesthesia?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273713/
https://www.ncbi.nlm.nih.gov/pubmed/24945286
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