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Theory-based analysis of clinical efficacy of triptans using receptor occupancy

BACKGROUND: Triptans, serotonin 5-HT(1B/1D) receptor agonists, exert their action by targeting serotonin 5-HT(1B/1D) receptors, are used for treatment of migraine attack. Presently, 5 different triptans, namely sumatriptan, zolmitriptan, eletriptan, rizatriptan, and naratriptan, are marketed in Japa...

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Detalles Bibliográficos
Autores principales:	Tokuoka, Kentaro, Takayanagi, Risa, Suzuki, Yuji, Watanabe, Masayuki, Kitagawa, Yasuhisa, Yamada, Yasuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273730/ https://www.ncbi.nlm.nih.gov/pubmed/25488888 http://dx.doi.org/10.1186/1129-2377-15-85

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