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One-Step Biosynthesis of α-Keto-γ-Methylthiobutyric Acid from L-Methionine by an Escherichia coli Whole-Cell Biocatalyst Expressing an Engineered L-Amino Acid Deaminase from Proteus vulgaris
α-Keto-γ-methylthiobutyric acid (KMTB), a keto derivative of l-methionine, has great potential for use as an alternative to l-methionine in the poultry industry and as an anti-cancer drug. This study developed an environment friendly process for KMTB production from l-methionine by an Escherichia co...
Autores principales: | Hossain, Gazi Sakir, Li, Jianghua, Shin, Hyun-dong, Du, Guocheng, Wang, Miao, Liu, Long, Chen, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273966/ https://www.ncbi.nlm.nih.gov/pubmed/25531756 http://dx.doi.org/10.1371/journal.pone.0114291 |
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