Carbon-Ion Beam Irradiation Kills X-Ray-Resistant p53-Null Cancer Cells by Inducing Mitotic Catastrophe

BACKGROUND AND PURPOSE: To understand the mechanisms involved in the strong killing effect of carbon-ion beam irradiation on cancer cells with TP53 tumor suppressor gene deficiencies. MATERIALS AND METHODS: DNA damage responses after carbon-ion beam or X-ray irradiation in isogenic HCT116 colorectal...

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Detalles Bibliográficos
Autores principales: Amornwichet, Napapat, Oike, Takahiro, Shibata, Atsushi, Ogiwara, Hideaki, Tsuchiya, Naoto, Yamauchi, Motohiro, Saitoh, Yuka, Sekine, Ryota, Isono, Mayu, Yoshida, Yukari, Ohno, Tatsuya, Kohno, Takashi, Nakano, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274003/
https://www.ncbi.nlm.nih.gov/pubmed/25531293
http://dx.doi.org/10.1371/journal.pone.0115121

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