Cargando…

Cathelicidin suppresses colon cancer development by inhibition of cancer associated fibroblasts

BACKGROUND: Cathelicidin (LL-37 in humans and mCRAMP in mice) represents a family of endogenous antimicrobial and anti-inflammatory peptides. Cancer-associated fibroblasts can promote the proliferation of colon cancer cells and growth of colon cancer tumors. METHODS: We examined the role of cathelic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Michelle, Ho, Samantha, Yoo, Jun Hwan, Tran, Deanna Hoang-Yen, Bakirtzi, Kyriaki, Su, Bowei, Tran, Diana Hoang-Ngoc, Kubota, Yuzu, Ichikawa, Ryan, Koon, Hon Wai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274046/ https://www.ncbi.nlm.nih.gov/pubmed/25565877 http://dx.doi.org/10.2147/CEG.S70906

Ejemplares similares

Antifibrogenic Effects of the Antimicrobial Peptide Cathelicidin in Murine Colitis-Associated Fibrosis
por: Yoo, Jun Hwan, et al.
Publicado: (2014)

Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor
por: Tran, Deanna Hoang-Yen, et al.
Publicado: (2016)

Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism
por: Wang, Jiani, et al.
Publicado: (2019)

Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohn’s disease, and clinical prognosis in inflammatory bowel disease
por: Tran, Diana Hoang-Ngoc, et al.
Publicado: (2017)

Substance P Mediates Proinflammatory Cytokine Release From Mesenteric Adipocytes in Inflammatory Bowel Disease Patients
por: Sideri, Aristea, et al.
Publicado: (2015)

Health-Related Quality of Life Among Vietnamese Breast Cancer Women
por: Tran, Thanh Huong, et al.
Publicado: (2019)

The Role of Cathelicidin LL-37 in Cancer Development
por: Piktel, Ewelina, et al.
Publicado: (2015)

Formation of the upper digestive tract by the ileum - right colon for patient with concurrent cancers of the esophagus and the stomach: A case report
por: Tran, Manh Hung, et al.
Publicado: (2021)

Magnetic nanoparticles enhance the anticancer activity of cathelicidin LL-37 peptide against colon cancer cells
por: Niemirowicz, Katarzyna, et al.
Publicado: (2015)

Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/β-catenin pathway
por: Li, Dong, et al.
Publicado: (2014)

A Simple, Effective, Green Method for the Regioselective 3-Acylation of Unprotected Indoles
por: Tran, Phuong Hoang, et al.
Publicado: (2015)

Cathelicidins Induce Toll-Interacting Protein Synthesis to Prevent Apoptosis in Colonic Epithelium
por: Holani, Ravi, et al.
Publicado: (2022)

Neurotensin—regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis
por: Law, Ivy Ka Man, et al.
Publicado: (2015)

Functional Implications of Cathelicidin Antimicrobial Protein in Breast Cancer and Tumor-Associated Macrophage Microenvironment
por: Chen, Jiawei, et al.
Publicado: (2020)

Cathelicidins: Immunomodulatory Antimicrobials
por: van Harten, Roel M., et al.
Publicado: (2018)

Cathelicidins and the Onset of Labour
por: Boeckel, Sara R. van, et al.
Publicado: (2019)

Single-Port Access Endoscopic Thyroidectomy via Axillary Approach for the Benign Thyroid Tumor: New Aspects from Vietnam
por: Phan, Hoang-Hiep, et al.
Publicado: (2021)

Identification of a Novel Substance P–Neurokinin-1 Receptor MicroRNA-221-5p Inflammatory Network in Human Colonic Epithelial Cells
por: Fang, Kai, et al.
Publicado: (2015)

Dodecapeptide Cathelicidins of Cetartiodactyla: Structure, Mechanism of Antimicrobial Action, and Synergistic Interaction With Other Cathelicidins
por: Bolosov, Ilia A., et al.
Publicado: (2021)

Development of an Artificial Intelligence-Based Breast Cancer Detection Model by Combining Mammograms and Medical Health Records
por: Trang, Nguyen Thi Hoang, et al.
Publicado: (2023)

Costs of breast cancer treatment incurred by women in Vietnam
por: Ngan, Tran Thu, et al.
Publicado: (2022)

Colonic epithelial cathelicidin (LL‐37) expression intensity is associated with progression of colorectal cancer and presence of CD8 (+) T cell infiltrate
por: Porter, Ross J, et al.
Publicado: (2021)

Human Cathelicidin Production by the Cervix
por: Frew, Lorraine, et al.
Publicado: (2014)

Cathelicidin impact on inflammatory cells
por: Agier, Justyna, et al.
Publicado: (2015)

Immunomodulatory Properties of Defensins and Cathelicidins
por: Bowdish, D. M. E., et al.
Publicado: (2006)

Quality of life profile of general Vietnamese population using EQ-5D-5L
por: Nguyen, Long Hoang, et al.
Publicado: (2017)

Strengthening breast cancer services in Vietnam: a mixed-methods study
por: Jenkins, Chris, et al.
Publicado: (2019)

Engineered Human Cathelicidin Antimicrobial Peptides Inhibit Ebola Virus Infection
por: Yu, Yangsheng, et al.
Publicado: (2020)

Novel Cathelicidins from Pigeon Highlights Evolutionary Convergence in Avain Cathelicidins and Functions in Modulation of Innate Immunity
por: Yu, Haining, et al.
Publicado: (2015)

Dietary Carotenoid Intakes and Prostate Cancer Risk: A Case-Control Study from Vietnam
por: Van Hoang, Dong, et al.
Publicado: (2018)

Experiences of accessing and using breast cancer services in Vietnam: a descriptive qualitative study
por: Jenkins, Chris, et al.
Publicado: (2020)

Biological Activities and Chemical Constituents of Essential Oils from Piper cubeba Bojer and Piper nigrum L.
por: Andriana, Yusuf, et al.
Publicado: (2019)

Imaging the antimicrobial mechanism(s) of cathelicidin-2
por: Schneider, Viktoria A. F., et al.
Publicado: (2016)

Cathelicidin Insufficiency in Patients with Fatal Leptospirosis
por: Lindow, Janet C., et al.
Publicado: (2016)

Cathelicidins in the Tasmanian devil (Sarcophilus harrisii)
por: Peel, E., et al.
Publicado: (2016)

Cathelicidins Modulate TLR-Activation and Inflammation
por: Scheenstra, Maaike R., et al.
Publicado: (2020)

Genetic diversity of Japanese quail cathelicidins
por: Ishige, Taichiro, et al.
Publicado: (2021)

Sex-specific colonic mitochondrial dysfunction in the indomethacin-induced inflammatory bowel disease model in rats
por: Hoang, Ngoc, et al.
Publicado: (2023)

Cancers in Vietnam—Burden and Control Efforts: A Narrative Scoping Review
por: Pham, Tung, et al.
Publicado: (2019)

Cathelicidin-BF, a Snake Cathelicidin-Derived Antimicrobial Peptide, Could Be an Excellent Therapeutic Agent for Acne Vulgaris
por: Wang, Yipeng, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_9o60i84bu4h3g6eo78e1vta0v2