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Chronic Exercise Increases Plasma Brain-Derived Neurotrophic Factor Levels, Pancreatic Islet Size, and Insulin Tolerance in a TrkB-Dependent Manner
BACKGROUND: Physical exercise improves glucose metabolism and insulin sensitivity. Brain-derived neurotrophic factor (BDNF) enhances insulin activity in diabetic rodents. Because physical exercise modifies BDNF production, this study aimed to investigate the effects of chronic exercise on plasma BDN...
Autores principales: | Jiménez-Maldonado, Alberto, de Álvarez-Buylla, Elena Roces, Montero, Sergio, Melnikov, Valery, Castro-Rodríguez, Elena, Gamboa-Domínguez, Armando, Rodríguez-Hernández, Alejandrina, Lemus, Mónica, Murguía, Jesús Muñiz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274083/ https://www.ncbi.nlm.nih.gov/pubmed/25531651 http://dx.doi.org/10.1371/journal.pone.0115177 |
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