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Phospholipase D activates HIF-1-VEGF pathway via phosphatidic acid

Growth factor-stimulated phospholipase D (PLD) catalyzes the hydrolysis of phosphatidylcholine (PC), generating phosphatidic acid (PA) which may act as a second messenger during cell proliferation and survival. Therefore, PLD is believed to play an important role in tumorigenesis. In this study, a p...

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Detalles Bibliográficos
Autores principales: Han, Songyi, Huh, Jeongsoon, Kim, Wooseong, Jeong, Seongkeun, Min, Do Sik, Jung, Yunjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274397/
https://www.ncbi.nlm.nih.gov/pubmed/25523098
http://dx.doi.org/10.1038/emm.2014.86