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High Prevalence of Clustered Tuberculosis Cases in Peruvian Migrants in Florence, Italy

Tuberculosis is a leading cause of morbidity for Peruvian migrants in Florence, Italy, where they account for about 20% of yearly diagnosed cases. A retrospective study on cases notified in Peruvian residents in Florence in the period 2001-2010 was carried out and available Mycobacterium tuberculosi...

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Autores principales: Zammarchi, Lorenzo, Tortoli, Enrico, Borroni, Emanuele, Bartalesi, Filippo, Strohmeyer, Marianne, Baretti, Simonetta, Simonetti, Maria Tullia, Liendo, Carola, Santini, Maria Grazia, Rossolini, Gian Maria, Gotuzzo, Eduardo, Bartoloni, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274404/
https://www.ncbi.nlm.nih.gov/pubmed/25568758
http://dx.doi.org/10.4081/idr.2014.5646
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author Zammarchi, Lorenzo
Tortoli, Enrico
Borroni, Emanuele
Bartalesi, Filippo
Strohmeyer, Marianne
Baretti, Simonetta
Simonetti, Maria Tullia
Liendo, Carola
Santini, Maria Grazia
Rossolini, Gian Maria
Gotuzzo, Eduardo
Bartoloni, Alessandro
author_facet Zammarchi, Lorenzo
Tortoli, Enrico
Borroni, Emanuele
Bartalesi, Filippo
Strohmeyer, Marianne
Baretti, Simonetta
Simonetti, Maria Tullia
Liendo, Carola
Santini, Maria Grazia
Rossolini, Gian Maria
Gotuzzo, Eduardo
Bartoloni, Alessandro
author_sort Zammarchi, Lorenzo
collection PubMed
description Tuberculosis is a leading cause of morbidity for Peruvian migrants in Florence, Italy, where they account for about 20% of yearly diagnosed cases. A retrospective study on cases notified in Peruvian residents in Florence in the period 2001-2010 was carried out and available Mycobacterium tuberculosis strains were genotyped (MIRU-VNTR-24 and Spoligotyping). One hundred thirty eight cases were retrieved. Genotyping performed in 87 strains revealed that 39 (44.8%) belonged to 12 clusters. Assuming that in each cluster the transmission of tuberculosis from the index case took place in Florence, a large proportion of cases could be preventable by improving early diagnosis of contagious cases and contact tracing.
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spelling pubmed-42744042015-01-07 High Prevalence of Clustered Tuberculosis Cases in Peruvian Migrants in Florence, Italy Zammarchi, Lorenzo Tortoli, Enrico Borroni, Emanuele Bartalesi, Filippo Strohmeyer, Marianne Baretti, Simonetta Simonetti, Maria Tullia Liendo, Carola Santini, Maria Grazia Rossolini, Gian Maria Gotuzzo, Eduardo Bartoloni, Alessandro Infect Dis Rep Brief Report Tuberculosis is a leading cause of morbidity for Peruvian migrants in Florence, Italy, where they account for about 20% of yearly diagnosed cases. A retrospective study on cases notified in Peruvian residents in Florence in the period 2001-2010 was carried out and available Mycobacterium tuberculosis strains were genotyped (MIRU-VNTR-24 and Spoligotyping). One hundred thirty eight cases were retrieved. Genotyping performed in 87 strains revealed that 39 (44.8%) belonged to 12 clusters. Assuming that in each cluster the transmission of tuberculosis from the index case took place in Florence, a large proportion of cases could be preventable by improving early diagnosis of contagious cases and contact tracing. PAGEPress Publications, Pavia, Italy 2014-12-11 /pmc/articles/PMC4274404/ /pubmed/25568758 http://dx.doi.org/10.4081/idr.2014.5646 Text en ©Copyright L. Zammarchi et al. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Zammarchi, Lorenzo
Tortoli, Enrico
Borroni, Emanuele
Bartalesi, Filippo
Strohmeyer, Marianne
Baretti, Simonetta
Simonetti, Maria Tullia
Liendo, Carola
Santini, Maria Grazia
Rossolini, Gian Maria
Gotuzzo, Eduardo
Bartoloni, Alessandro
High Prevalence of Clustered Tuberculosis Cases in Peruvian Migrants in Florence, Italy
title High Prevalence of Clustered Tuberculosis Cases in Peruvian Migrants in Florence, Italy
title_full High Prevalence of Clustered Tuberculosis Cases in Peruvian Migrants in Florence, Italy
title_fullStr High Prevalence of Clustered Tuberculosis Cases in Peruvian Migrants in Florence, Italy
title_full_unstemmed High Prevalence of Clustered Tuberculosis Cases in Peruvian Migrants in Florence, Italy
title_short High Prevalence of Clustered Tuberculosis Cases in Peruvian Migrants in Florence, Italy
title_sort high prevalence of clustered tuberculosis cases in peruvian migrants in florence, italy
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274404/
https://www.ncbi.nlm.nih.gov/pubmed/25568758
http://dx.doi.org/10.4081/idr.2014.5646
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