Prostatic Stromal Sarcoma in an Adolescent: The Role of Chemotherapy

Prostatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin...

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Autores principales: Cavaliere, Elena, Alaggio, Rita, Castagnetti, Marco, Scarzello, Giovanni, Bisogno, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274447/
https://www.ncbi.nlm.nih.gov/pubmed/25568753
http://dx.doi.org/10.4081/rt.2014.5607
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author Cavaliere, Elena
Alaggio, Rita
Castagnetti, Marco
Scarzello, Giovanni
Bisogno, Gianni
author_facet Cavaliere, Elena
Alaggio, Rita
Castagnetti, Marco
Scarzello, Giovanni
Bisogno, Gianni
author_sort Cavaliere, Elena
collection PubMed
description Prostatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin-D, although the final outcome was dismal. A review of the English literature revealed 14 additional patients with PSS treated with chemotherapy: tumor shrinkage was reported in 4 of the 6 evaluable patients. Patients with PSS may benefit from the use of chemotherapy in combination with early aggressive local treatment.
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spelling pubmed-42744472015-01-07 Prostatic Stromal Sarcoma in an Adolescent: The Role of Chemotherapy Cavaliere, Elena Alaggio, Rita Castagnetti, Marco Scarzello, Giovanni Bisogno, Gianni Rare Tumors Case Report Prostatic stromal sarcoma (PSS) is a rare tumor that normally occurs in adult age. Its management relies mainly on surgery. We report the first case of PSS occurring in an adolescent. There was evidence of a good response to chemotherapy including ifosfamide, doxorubicin, vincristine and actinomycin-D, although the final outcome was dismal. A review of the English literature revealed 14 additional patients with PSS treated with chemotherapy: tumor shrinkage was reported in 4 of the 6 evaluable patients. Patients with PSS may benefit from the use of chemotherapy in combination with early aggressive local treatment. PAGEPress Publications, Pavia, Italy 2014-12-18 /pmc/articles/PMC4274447/ /pubmed/25568753 http://dx.doi.org/10.4081/rt.2014.5607 Text en ©Copyright E. Cavaliere et al. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Cavaliere, Elena
Alaggio, Rita
Castagnetti, Marco
Scarzello, Giovanni
Bisogno, Gianni
Prostatic Stromal Sarcoma in an Adolescent: The Role of Chemotherapy
title Prostatic Stromal Sarcoma in an Adolescent: The Role of Chemotherapy
title_full Prostatic Stromal Sarcoma in an Adolescent: The Role of Chemotherapy
title_fullStr Prostatic Stromal Sarcoma in an Adolescent: The Role of Chemotherapy
title_full_unstemmed Prostatic Stromal Sarcoma in an Adolescent: The Role of Chemotherapy
title_short Prostatic Stromal Sarcoma in an Adolescent: The Role of Chemotherapy
title_sort prostatic stromal sarcoma in an adolescent: the role of chemotherapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274447/
https://www.ncbi.nlm.nih.gov/pubmed/25568753
http://dx.doi.org/10.4081/rt.2014.5607
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