Vasculitis and long standing ankylosing spondylitis in a patient with familial Mediterranean fever

Coexistence of familial Mediterranean fever (FMF) and other inflammatory disorders has been frequently reported, but no specific underlying factor has been identified. We report a patient with FMF who is presented with long-standing ankylosing spondylitis (AS) and cutaneous leukocytoklastic vasculit...

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Autores principales: Taylan, Ali, Yildiz, Yasar, Sari, Ismail, Ozkok, Guliz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274560/
https://www.ncbi.nlm.nih.gov/pubmed/25538787
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author Taylan, Ali
Yildiz, Yasar
Sari, Ismail
Ozkok, Guliz
author_facet Taylan, Ali
Yildiz, Yasar
Sari, Ismail
Ozkok, Guliz
author_sort Taylan, Ali
collection PubMed
description Coexistence of familial Mediterranean fever (FMF) and other inflammatory disorders has been frequently reported, but no specific underlying factor has been identified. We report a patient with FMF who is presented with long-standing ankylosing spondylitis (AS) and cutaneous leukocytoklastic vasculitis (LV) of the lower limbs. It is the first report on combination of FMF with AS and LV. The Mediterranean Fever (MEFV) gene mutation of heterozygote (R202Q/R726A) and HLA-B27 are detected in this case, and are believed to form genetic susceptibility to LV.
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spelling pubmed-42745602014-12-23 Vasculitis and long standing ankylosing spondylitis in a patient with familial Mediterranean fever Taylan, Ali Yildiz, Yasar Sari, Ismail Ozkok, Guliz J Res Med Sci Case Report Coexistence of familial Mediterranean fever (FMF) and other inflammatory disorders has been frequently reported, but no specific underlying factor has been identified. We report a patient with FMF who is presented with long-standing ankylosing spondylitis (AS) and cutaneous leukocytoklastic vasculitis (LV) of the lower limbs. It is the first report on combination of FMF with AS and LV. The Mediterranean Fever (MEFV) gene mutation of heterozygote (R202Q/R726A) and HLA-B27 are detected in this case, and are believed to form genetic susceptibility to LV. Medknow Publications & Media Pvt Ltd 2014-10 /pmc/articles/PMC4274560/ /pubmed/25538787 Text en Copyright: © Journal of Research in Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Taylan, Ali
Yildiz, Yasar
Sari, Ismail
Ozkok, Guliz
Vasculitis and long standing ankylosing spondylitis in a patient with familial Mediterranean fever
title Vasculitis and long standing ankylosing spondylitis in a patient with familial Mediterranean fever
title_full Vasculitis and long standing ankylosing spondylitis in a patient with familial Mediterranean fever
title_fullStr Vasculitis and long standing ankylosing spondylitis in a patient with familial Mediterranean fever
title_full_unstemmed Vasculitis and long standing ankylosing spondylitis in a patient with familial Mediterranean fever
title_short Vasculitis and long standing ankylosing spondylitis in a patient with familial Mediterranean fever
title_sort vasculitis and long standing ankylosing spondylitis in a patient with familial mediterranean fever
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274560/
https://www.ncbi.nlm.nih.gov/pubmed/25538787
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