Effects of whole-body vibration training on fibrinolytic and coagulative factors in healthy young men

BACKGROUND: The aim was to evaluate effects of 5-week whole body vibration (WBV) training with different amplitudes and progressive frequencies on fibrinolytic/coagulative factors. MATERIALS AND METHODS: 25 subjects were divided randomly in high or low-amplitude vibration, and control groups. Training consisted of 5-week WBV with amplitudes 4 or 2 mm. Plasma samples were analyzed before and after training. Statistical analysis was done using one-way analysis of variance and Wilcoxon signed ranked test. P <0.05 was considered significant. RESULTS: High-amplitude vibration caused an increase in tissue plasminogen activator (tPA) (P = 0.028) (pretest: 1744.61 ± 707.95; posttest: 2313.63 ± 997.19 pg/ml), and decrease in plasminogen activator inhibitor-1 (PAI-1) (P = 0.033) (pretest: 97.94 ± 34.37; posttest: 85.12 ± 36.92 ng/ml). Fibrinogen and plasminogen were not changed significantly. Low-amplitude vibration caused an increase in tPA (P = 0.006) (pretest: 2208.18 ± 1280.37; posttest: 3492.72 ± 3549.22 pg/ml). PAI-1, fibrinogen and plasminogen were not changed significantly. There were no significant differences between groups. CONCLUSION: Amplitude of vibrations in WBV training may affect fibrinolytic factors.