Transient Antiphospholipid Syndrome Associated with Primary Cytomegalovirus Infection: A Case Report and Literature Review

Viral infection is known to induce transient autoimmunity in humans. Acute cytomegalovirus (CMV) infection is implicated in occasional thrombosis formation. We here, for the first time, report a 19-year-old female who had an acute CMV infection, leading to a deep venous thrombosis and a pulmonary em...

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Detalles Bibliográficos
Autores principales: Nakayama, Tsuyoshi, Akahoshi, Mitsuteru, Irino, Kensuke, Kimoto, Yasutaka, Arinobu, Yojiro, Niiro, Hiroaki, Tsukamoto, Hiroshi, Horiuchi, Takahiko, Akashi, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274647/
https://www.ncbi.nlm.nih.gov/pubmed/25548710
http://dx.doi.org/10.1155/2014/271548
Descripción
Sumario:Viral infection is known to induce transient autoimmunity in humans. Acute cytomegalovirus (CMV) infection is implicated in occasional thrombosis formation. We here, for the first time, report a 19-year-old female who had an acute CMV infection, leading to a deep venous thrombosis and a pulmonary embolism along with transient appearance of lupus anticoagulant. The pathological role of antiphospholipid antibodies in CMV-mediated thrombosis is discussed.

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