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Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease
Objective. This study aimed to evaluate the CT features of incidentally detected DTD in the patients who underwent thyroidectomy and to assess the diagnostic accuracy of CT diagnosis. Methods. We enrolled 209 consecutive patients who received preoperative neck CT and subsequent thyroid surgery. Neck...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274648/ https://www.ncbi.nlm.nih.gov/pubmed/25548565 http://dx.doi.org/10.1155/2014/921934 |
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author | Rho, Myung Ho Kim, Dong Wook |
author_facet | Rho, Myung Ho Kim, Dong Wook |
author_sort | Rho, Myung Ho |
collection | PubMed |
description | Objective. This study aimed to evaluate the CT features of incidentally detected DTD in the patients who underwent thyroidectomy and to assess the diagnostic accuracy of CT diagnosis. Methods. We enrolled 209 consecutive patients who received preoperative neck CT and subsequent thyroid surgery. Neck CT in each case was retrospectively investigated by a single radiologist. We evaluated the diagnostic accuracy of individual CT features and the cut-off CT criteria for detecting DTD by comparing the CT features with histopathological results. Results. Histopathological examination of the 209 cases revealed normal thyroid (n = 157), Hashimoto thyroiditis (n = 17), non-Hashimoto lymphocytic thyroiditis (n = 34), and diffuse hyperplasia (n = 1). The CT features suggestive of DTD included low attenuation, inhomogeneous attenuation, increased glandular size, lobulated margin, and inhomogeneous enhancement. ROC curve analysis revealed that CT diagnosis of DTD based on the CT classification of “3 or more” abnormal CT features was superior. When the “3 or more” CT classification was selected, the sensitivity, specificity, positive and negative predictive values, and accuracy of CT diagnosis for DTD were 55.8%, 95.5%, 80.6%, 86.7%, and 85.6%, respectively. Conclusion. Neck CT may be helpful for the detection of incidental DTD. |
format | Online Article Text |
id | pubmed-4274648 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-42746482014-12-29 Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease Rho, Myung Ho Kim, Dong Wook Int J Endocrinol Research Article Objective. This study aimed to evaluate the CT features of incidentally detected DTD in the patients who underwent thyroidectomy and to assess the diagnostic accuracy of CT diagnosis. Methods. We enrolled 209 consecutive patients who received preoperative neck CT and subsequent thyroid surgery. Neck CT in each case was retrospectively investigated by a single radiologist. We evaluated the diagnostic accuracy of individual CT features and the cut-off CT criteria for detecting DTD by comparing the CT features with histopathological results. Results. Histopathological examination of the 209 cases revealed normal thyroid (n = 157), Hashimoto thyroiditis (n = 17), non-Hashimoto lymphocytic thyroiditis (n = 34), and diffuse hyperplasia (n = 1). The CT features suggestive of DTD included low attenuation, inhomogeneous attenuation, increased glandular size, lobulated margin, and inhomogeneous enhancement. ROC curve analysis revealed that CT diagnosis of DTD based on the CT classification of “3 or more” abnormal CT features was superior. When the “3 or more” CT classification was selected, the sensitivity, specificity, positive and negative predictive values, and accuracy of CT diagnosis for DTD were 55.8%, 95.5%, 80.6%, 86.7%, and 85.6%, respectively. Conclusion. Neck CT may be helpful for the detection of incidental DTD. Hindawi Publishing Corporation 2014 2014-12-08 /pmc/articles/PMC4274648/ /pubmed/25548565 http://dx.doi.org/10.1155/2014/921934 Text en Copyright © 2014 M. H. Rho and D. W. Kim. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Rho, Myung Ho Kim, Dong Wook Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease |
title | Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease |
title_full | Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease |
title_fullStr | Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease |
title_full_unstemmed | Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease |
title_short | Computed Tomography Features of Incidentally Detected Diffuse Thyroid Disease |
title_sort | computed tomography features of incidentally detected diffuse thyroid disease |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274648/ https://www.ncbi.nlm.nih.gov/pubmed/25548565 http://dx.doi.org/10.1155/2014/921934 |
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