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An integrated transcriptome and expressed variant analysis of sepsis survival and death
BACKGROUND: Sepsis, a leading cause of morbidity and mortality, is not a homogeneous disease but rather a syndrome encompassing many heterogeneous pathophysiologies. Patient factors including genetics predispose to poor outcomes, though current clinical characterizations fail to identify those at gr...
Autores principales: | Tsalik, Ephraim L, Langley, Raymond J, Dinwiddie, Darrell L, Miller, Neil A, Yoo, Byunggil, van Velkinburgh, Jennifer C, Smith, Laurie D, Thiffault, Isabella, Jaehne, Anja K, Valente, Ashlee M, Henao, Ricardo, Yuan, Xin, Glickman, Seth W, Rice, Brandon J, McClain, Micah T, Carin, Lawrence, Corey, G Ralph, Ginsburg, Geoffrey S, Cairns, Charles B, Otero, Ronny M, Fowler, Vance G, Rivers, Emanuel P, Woods, Christopher W, Kingsmore, Stephen F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274761/ https://www.ncbi.nlm.nih.gov/pubmed/25538794 http://dx.doi.org/10.1186/s13073-014-0111-5 |
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