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Neuronal T-Cell Autoreactivity Is Amplified in Overweight Children With New-Onset Insulin-Requiring Diabetes
OBJECTIVE: Disease-associated T-cell autoreactivities are seen in most type 1 diabetic patients and are thought to emerge before islet autoantibodies, but host factors that impact autoimmune elements remain uncertain. We assessed if adiposity and measures of insulin sensitivity impact T- and B-cell...
Autores principales: | Buryk, Melissa A., Dosch, H-Michael, Libman, Ingrid, Arena, Vincent C., Huang, Yihe, Cheung, Roy K., Trucco, Massimo, Pietropaolo, Massimo, Becker, Dorothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274776/ https://www.ncbi.nlm.nih.gov/pubmed/25414154 http://dx.doi.org/10.2337/dc14-1861 |
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