Cargando…

Multisite Kinetic Modeling of (13)C Metabolic MR Using [1-(13)C]Pyruvate

Hyperpolarized (13)C imaging allows real-time in vivo measurements of metabolite levels. Quantification of metabolite conversion between [1-(13)C]pyruvate and downstream metabolites [1-(13)C]alanine, [1-(13)C]lactate, and [(13)C]bicarbonate can be achieved through kinetic modeling. Since pyruvate in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gómez Damián, Pedro A., Sperl, Jonathan I., Janich, Martin A., Khegai, Oleksandr, Wiesinger, Florian, Glaser, Steffen J., Haase, Axel, Schwaiger, Markus, Schulte, Rolf F., Menzel, Marion I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274847/ https://www.ncbi.nlm.nih.gov/pubmed/25548671 http://dx.doi.org/10.1155/2014/871619

Ejemplares similares

Hyperpolarized (13)C Diffusion MRS of Co-Polarized Pyruvate and Fumarate to Measure Lactate Export and Necrosis
por: Feuerecker, Benedikt, et al.
Publicado: (2017)

A comparison of quantitative methods for clinical imaging with hyperpolarized (13)C‐pyruvate
por: Daniels, Charlie J., et al.
Publicado: (2016)

Investigation of metabolic changes in STZ-induced diabetic rats with hyperpolarized [1-13C]acetate
por: Koellisch, Ulrich, et al.
Publicado: (2015)

Detection of 3D Cardiac metabolism after injection of hyperpolarized [1-13C]pyruvate
por: Frijia, Francesca, et al.
Publicado: (2011)

Analysis of (13)C and (14)C labeling in pyruvate and lactate in tumor and blood of lymphoma‐bearing mice injected with (13)C‐ and (14)C‐labeled pyruvate
por: Serrao, E.M., et al.
Publicado: (2018)

Simultaneous assessment of cardiac metabolism and perfusion using copolarized [1‐(13)C]pyruvate and (13)C‐urea
por: Lau, Angus Z., et al.
Publicado: (2016)

[(13)C]bicarbonate labelled from hyperpolarized [1-(13)C]pyruvate is an in vivo marker of hepatic gluconeogenesis in fasted state
por: Can, Emine, et al.
Publicado: (2022)

Imaging of pH in vivo using hyperpolarized (13)C-labelled zymonic acid
por: Düwel, Stephan, et al.
Publicado: (2017)

Segmental analysis of cardiac metabolism by hyperpolarized [1-13C] pyruvate: an in-vivo 3D MRI study in pigs
por: Positano, Vincenzo, et al.
Publicado: (2012)

Current state‐of‐the‐art hyperpolarized (13)C‐acetate‐to‐acetylcarnitine imaging is not indicative of the altered balance between glucose and fatty acid utilization associated with diabetes
por: Koellisch, Ulrich, et al.
Publicado: (2016)

Synthesis of (13)C and (2)H Labeled Vinyl Pyruvate and Hyperpolarization of Pyruvate
por: Brahms, Arne, et al.
Publicado: (2022)

(13)C magnetic resonance spectroscopy measurements with hyperpolarized [1‐(13)C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo
por: Dzien, Piotr, et al.
Publicado: (2015)

Hyperpolarized (13)C pyruvate magnetic resonance spectroscopy for in vivo metabolic phenotyping of rat HCC
por: Bliemsrieder, Elisabeth, et al.
Publicado: (2021)

Lactate saturation limits bicarbonate detection in hyperpolarized (13)C‐pyruvate MRI of the brain
por: Bøgh, Nikolaj, et al.
Publicado: (2022)

In Vivo Assessment of Metabolic Abnormality in Alport Syndrome Using Hyperpolarized [1-(13)C] Pyruvate MR Spectroscopic Imaging
por: Nguyen, Nguyen-Trong, et al.
Publicado: (2021)

3D cardiac Chemical Shift Imaging of [1-13C] hyperpolarized acetate and pyruvate in pigs
por: Menichetti, Luca, et al.
Publicado: (2013)

Probing hepatic metabolism of [2-(13)C]dihydroxyacetone in vivo with (1)H-decoupled hyperpolarized (13)C-MR
por: Marco-Rius, Irene, et al.
Publicado: (2020)

PHIP hyperpolarized [1-(13)C]pyruvate and [1-(13)C]acetate esters via PH-INEPT polarization transfer monitored by (13)C NMR and MRI
por: Svyatova, Alexandra, et al.
Publicado: (2021)

Detection of increased pyruvate dehydrogenase flux in the human heart during adenosine stress test using hyperpolarized [1-(13)C]pyruvate cardiovascular magnetic resonance imaging
por: Joergensen, Steen Hylgaard, et al.
Publicado: (2022)

Pyruvate Carboxylation in Different Model Systems Studied by (13)C MRS
por: Sonnewald, Ursula, et al.
Publicado: (2010)

(13)C Pyruvate Transport Across the Blood-Brain Barrier in Preclinical Hyperpolarised MRI
por: Miller, Jack J., et al.
Publicado: (2018)

Mapping of intracellular pH in the in vivo rodent heart using hyperpolarized [1‐13C]pyruvate
por: Lau, Angus Z., et al.
Publicado: (2016)

Quantifying normal human brain metabolism using hyperpolarized [1–(13)C]pyruvate and magnetic resonance imaging
por: Grist, James T., et al.
Publicado: (2019)

Effects of fasting on serial measurements of hyperpolarized [1‐(13)C]pyruvate metabolism in tumors
por: Serrao, Eva M., et al.
Publicado: (2016)

Assessing the effect of anesthetic gas mixtures on hyperpolarized (13) C pyruvate metabolism in the rat brain
por: Healicon, Richard, et al.
Publicado: (2022)

Assessment of Metformin induced changes in cardiac redox state using hyperpolarized[1-(13)C]pyruvate
por: Lewis, Andrew, et al.
Publicado: (2016)

Author Correction: Hyperpolarized (13)C pyruvate magnetic resonance spectroscopy for in vivo metabolic phenotyping of rat HCC
por: Bliemsrieder, Elisabeth, et al.
Publicado: (2021)

Detecting treatment response in a model of human breast adenocarcinoma using hyperpolarised [1-(13)C]pyruvate and [1,4-(13)C(2)]fumarate
por: Witney, T H, et al.
Publicado: (2010)

In Vivo Carbon-13 Dynamic MRS and MRSI of Normal and Fasted Rat Liver with Hyperpolarized (13)C-Pyruvate
por: Hu, Simon, et al.
Publicado: (2009)

Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate
por: Bastiaansen, Jessica A. M., et al.
Publicado: (2016)

Metabolic alterations in acute myocardial ischemia-reperfusion injury and necrosis using in vivo hyperpolarized [1-(13)C] pyruvate MR spectroscopy
por: Moon, Chung-Man, et al.
Publicado: (2019)

Probing Human Heart TCA Cycle Metabolism and Response to Glucose Load using Hyperpolarized [2-(13)C]Pyruvate MR Spectroscopy
por: Chen, Hsin-Yu, et al.
Publicado: (2023)

Assessment of (213)Bi-anti-EGFR MAb treatment efficacy in malignant cancer cells with [1-(13)C]pyruvate and [(18)F]FDG
por: Feuerecker, Benedikt, et al.
Publicado: (2019)

Potential Clinical Roles for Metabolic Imaging with Hyperpolarized [1-(13)C]Pyruvate
por: Serrao, Eva M., et al.
Publicado: (2016)

Molecular detection of inflammation in cell models using hyperpolarized (13)C-pyruvate
por: Sriram, Renuka, et al.
Publicado: (2018)

Current Methods for Hyperpolarized [1-13C]pyruvate MRI Human Studies
por: Larson, Peder EZ, et al.
Publicado: (2023)

Assessment of Aspartate and Bicarbonate Produced From Hyperpolarized [1-(13)C]Pyruvate as Markers of Renal Gluconeogenesis
por: Yoshihara, Hikari A. I., et al.
Publicado: (2021)

Metabolite-Specific Echo Planar Imaging for Preclinical Studies with Hyperpolarized (13)C-Pyruvate MRI
por: Sahin, Sule I., et al.
Publicado: (2023)

Simultaneous characterization of tumor cellularity and the Warburg effect with PET, MRI and hyperpolarized (13)C-MRSI
por: Hundshammer, Christian, et al.
Publicado: (2018)

A referenceless Nyquist ghost correction workflow for echo planar imaging of hyperpolarized [1‐(13)C]pyruvate and [1‐(13)C]lactate
por: Wang, Jiazheng, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_239kv6cmasoev2kr4ul0atcv7r