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The CCR5Δ32 Polymorphism in Brazilian Patients with Sickle Cell Disease
Background. Previous studies on the role of inflammation in the pathophysiology of sickle cell disease (SCD) suggested that the CCR5Δ32 allele, which is responsible for the production of truncated C-C chemokine receptor type 5 (CCR5), could confer a selective advantage on patients with SCD because i...
Autores principales: | Lopes, Mariana Pezzute, Santos, Magnun Nueldo Nunes, Faber, Eliel Wagner, Bezerra, Marcos André Cavalcanti, Hatzlhofer, Betânia Lucena Domingues, Albuquerque, Dulcinéia Martins, Zaccariotto, Tânia Regina, Ribeiro, Daniela Maria, Araújo, Aderson da Silva, Costa, Fernando Ferreira, Sonati, Maria de Fátima |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274860/ https://www.ncbi.nlm.nih.gov/pubmed/25548430 http://dx.doi.org/10.1155/2014/678246 |
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