Drug susceptibility profile and pathogenicity of H7N9 influenza virus (Anhui1 lineage) with R292K substitution

Neuraminidase inhibitors (NAIs) are the only available licensed therapeutics against human H7N9 influenza virus infections. The emergence of NAI-resistant variants of H7N9viruses with an NA R292K mutation poses a therapeutic challenge. A comprehensive understanding of the susceptibility of these vir...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaonan, Song, Zhigang, He, Jing, Yen, Hui-Ling, Li, Jianhua, Zhu, Zhaoqin, Tian, Di, Wang, Wei, Xu, Lei, Guan, Wencai, Liu, Yi, Wang, Sen, Shi, Bisheng, Zhang, Wanju, Qin, Boyin, Cai, Jialin, Wan, Yanmin, Xu, Chunhua, Ren, Xiaonan, Chen, Haili, Liu, Lu, Yang, Yuqin, Zhou, Xiaohui, Zhou, Wenjiang, Xu, Jianqing, Zhang, Xiaoyan, Peiris, Malik, Hu, Yunwen, Yuan, Zhenghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274890/
https://www.ncbi.nlm.nih.gov/pubmed/26038501
http://dx.doi.org/10.1038/emi.2014.80

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