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Androgen-Targeted Therapy-Induced Epithelial Mesenchymal Plasticity and Neuroendocrine Transdifferentiation in Prostate Cancer: An Opportunity for Intervention
Androgens regulate biological pathways to promote proliferation, differentiation, and survival of benign and malignant prostate tissue. Androgen receptor (AR) targeted therapies exploit this dependence and are used in advanced prostate cancer to control disease progression. Contemporary treatment re...
Autores principales: | Nouri, Mannan, Ratther, Ellca, Stylianou, Nataly, Nelson, Colleen C., Hollier, Brett G., Williams, Elizabeth D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274903/ https://www.ncbi.nlm.nih.gov/pubmed/25566507 http://dx.doi.org/10.3389/fonc.2014.00370 |
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