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Effect of telmisartan on levels of IL-1, TNF-α, down-regulated COX-2, MMP-2, MMP-9 and RANKL/RANK in an experimental periodontitis model

AIM: The aim of this study was to evaluate the effect of telmisartan (TELM) on inflammation, oxidation and the expression of matrix metalloproteinases (MMPs) and the expression RANKL/RANK/OPG in the periodontal tissue of a rat model for ligature-induced periodontitis. MATERIALS AND METHODS: Male Wis...

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Detalles Bibliográficos
Autores principales: Araújo, Aurigena A, Souza, Tatiana O, Moura, Lígia M, Brito, Gerly A C, Aragão, Karoline S, Araújo, Lorena S, Medeiros, Caroline A X, Alves, Maria S C F, Araújo, Raimundo F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274974/
https://www.ncbi.nlm.nih.gov/pubmed/24118063
http://dx.doi.org/10.1111/jcpe.12160