Cargando…

Effect of telmisartan on levels of IL-1, TNF-α, down-regulated COX-2, MMP-2, MMP-9 and RANKL/RANK in an experimental periodontitis model

AIM: The aim of this study was to evaluate the effect of telmisartan (TELM) on inflammation, oxidation and the expression of matrix metalloproteinases (MMPs) and the expression RANKL/RANK/OPG in the periodontal tissue of a rat model for ligature-induced periodontitis. MATERIALS AND METHODS: Male Wis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Araújo, Aurigena A, Souza, Tatiana O, Moura, Lígia M, Brito, Gerly A C, Aragão, Karoline S, Araújo, Lorena S, Medeiros, Caroline A X, Alves, Maria S C F, Araújo, Raimundo F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2013
Materias:	Periodontal Diseases
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274974/ https://www.ncbi.nlm.nih.gov/pubmed/24118063 http://dx.doi.org/10.1111/jcpe.12160

Ejemplares similares

Olmesartan Decreased Levels of IL-1β and TNF-α, Down-Regulated MMP-2, MMP-9, COX-2, RANK/RANKL and Up-Regulated SOCs-1 in an Intestinal Mucositis Model
por: de Araújo Júnior, Raimundo Fernandes, et al.
Publicado: (2014)

Azilsartan Increases Levels of IL-10, Down-Regulates MMP-2, MMP-9, RANKL/RANK, Cathepsin K and Up-Regulates OPG in an Experimental Periodontitis Model
por: de Araújo, Aurigena Antunes, et al.
Publicado: (2014)

Carvedilol Decrease IL-1β and TNF-α, Inhibits MMP-2, MMP-9, COX-2, and RANKL Expression, and Up-Regulates OPG in a Rat Model of Periodontitis
por: de Araújo Júnior, Raimundo Fernandes, et al.
Publicado: (2013)

Telmisartan Modulates the Oral Mucositis Induced by 5-Fluorouracil in Hamsters
por: Barbosa, Maisie M., et al.
Publicado: (2018)

Azilsartan Reduced TNF-α and IL-1β Levels, Increased IL-10 Levels and Upregulated VEGF, FGF, KGF, and TGF-α in an Oral Mucositis Model
por: de Araújo, Aurigena Antunes, et al.
Publicado: (2015)

Correction: Olmesartan Decreased Levels of IL-1β and TNF-α, Down-Regulated MMP-2, MMP-9, COX-2, RANK/RANKL and Up-Regulated SOCs-1 in an Intestinal Mucositis Model
Publicado: (2015)

Effect of environmental tobacco smoke on COX‐2 and SHP‐2 expression in a periodontitis rat model
por: Li, Xiangjun, et al.
Publicado: (2020)

Contemporary periodontics /
Publicado: (1990)

RANKL/RANK/MMP-1 Molecular Triad Contributes to the Metastatic Phenotype of Breast and Prostate Cancer Cells In Vitro
por: Casimiro, Sandra, et al.
Publicado: (2013)

Effects of Bifidobacterium probiotic on the treatment of chronic periodontitis: A randomized clinical trial
por: Invernici, Marcos M., et al.
Publicado: (2018)

Self-report models for detection of periodontal diseases: Systematic review
por: Russell Hernández, Miguel Hazael, et al.
Publicado: (2021)

Site‐specific treatment outcome in smokers following 12 months of supportive periodontal therapy
por: Bunæs, Dagmar F., et al.
Publicado: (2016)

Site‐specific treatment outcome in smokers following non‐surgical and surgical periodontal therapy
por: Bunæs, Dagmar F., et al.
Publicado: (2015)

Subgingival air-polishing with erythritol during periodontal maintenance: Randomized clinical trial of twelve months
por: Müller, Nada, et al.
Publicado: (2014)

Lipoxin suppresses inflammation via the TLR4/MyD88/NF‐κB pathway in periodontal ligament cells
por: Ali, Muhanad, et al.
Publicado: (2019)

More teeth in more elderly: Periodontal treatment needs in Germany 1997–2030
por: Schwendicke, Falk, et al.
Publicado: (2018)

Effect of periodontal therapy with systemic antimicrobials on parameters of metabolic syndrome: A randomized clinical trial
por: Bizzarro, Sergio, et al.
Publicado: (2017)

Periodontal regeneration via chemoattractive constructs
por: Cai, Xinjie, et al.
Publicado: (2018)

Effectiveness of a calcium sodium phosphosilicate containing prophylaxis paste in reducing dentine hypersensitivity immediately and 4 weeks after a single application: a double-blind randomized controlled trial
por: Neuhaus, Klaus W, et al.
Publicado: (2013)

Biology of RANK, RANKL, and osteoprotegerin
por: Boyce, Brendan F, et al.
Publicado: (2007)

Adjunctive daily supplementation with encapsulated fruit, vegetable and berry juice powder concentrates and clinical periodontal outcomes: a double-blind RCT
por: Chapple, Iain L C, et al.
Publicado: (2012)

Association between obesity and periodontal disease in young adults: a population-based birth cohort
por: Dickie de Castilhos, Eduardo, et al.
Publicado: (2012)

Multiple applications of flurbiprofen and chlorhexidine chips in patients with chronic periodontitis: a randomized, double blind, parallel, 2-arms clinical trial
por: Machtei, Eli E, et al.
Publicado: (2011)

Comparing clinical attachment level and pocket depth for predicting periodontal disease progression in healthy sites of patients with chronic periodontitis using multi-state Markov models
por: Mdala, Ibrahimu, et al.
Publicado: (2014)

Gender differences in the association between metabolic syndrome and periodontal disease: the Hisayama Study
por: Furuta, Michiko, et al.
Publicado: (2013)

Clinical and microbiological effects of Lactobacillus reuteri probiotics in the treatment of chronic periodontitis: a randomized placebo-controlled study
por: Teughels, Wim, et al.
Publicado: (2013)

A randomized trial of ethyl lauroyl arginate‐containing mouthrinse in the control of gingivitis
por: Gallob, John T., et al.
Publicado: (2015)

Impaired neutrophil directional chemotactic accuracy in chronic periodontitis patients
por: Roberts, Helen M, et al.
Publicado: (2015)

Predictors of tooth loss due to periodontal disease in patients following long‐term periodontal maintenance
por: Martinez‐Canut, Pedro
Publicado: (2015)

Is progression of periodontitis relevantly influenced by systemic antibiotics? A clinical randomized trial
por: Harks, Inga, et al.
Publicado: (2015)

Three‐year randomized study of manual and power toothbrush effects on pre‐existing gingival recession
por: Dörfer, Christof E., et al.
Publicado: (2016)

Evaluation of a topical herbal patch for soft tissue wound healing: an animal study
por: Chaushu, Liat, et al.
Publicado: (2015)

Modelling changes in clinical attachment loss to classify periodontal disease progression
por: Teles, Ricardo, et al.
Publicado: (2016)

Longitudinal quantification of the gingival crevicular fluid proteome during progression from gingivitis to periodontitis in a canine model
por: Davis, Ian J., et al.
Publicado: (2016)

Regenerative potential of leucocyte‐ and platelet‐rich fibrin. Part A: intra‐bony defects, furcation defects and periodontal plastic surgery. A systematic review and meta‐analysis
por: Castro, Ana B., et al.
Publicado: (2016)

A comprehensive approach to assigning periodontal prognosis
por: Martinez‐Canut, Pedro, et al.
Publicado: (2018)

Xenogenic collagen matrix or autologous connective tissue graft as adjunct to coronally advanced flaps for coverage of multiple adjacent gingival recession: Randomized trial assessing non‐inferiority in root coverage and superiority in oral health‐related quality of life
por: Tonetti, Maurizio S., et al.
Publicado: (2017)

Introduction of a prediction model to assigning periodontal prognosis based on survival time
por: Martinez‐Canut, Pedro, et al.
Publicado: (2017)

Association of flossing/inter‐dental cleaning and periodontitis in adults
por: Cepeda, M. Soledad, et al.
Publicado: (2017)

Investigation of factors that influence pain experienced and the use of pain medication following periodontal surgery
por: Beaudette, Jennifer R., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4ptm159nuu19podin3nt5f40m8