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Discovery of functional non-coding conserved regions in the α-synuclein gene locus

Several single nucleotide polymorphisms (SNPs) and the Rep-1 microsatellite marker of the α-synuclein ( SNCA) gene have consistently been shown to be associated with Parkinson’s disease, but the functional relevance is unclear. Based on these findings we hypothesized that conserved cis-regulatory el...

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Detalles Bibliográficos
Autores principales: Sterling, Lori, Walter, Michael, Ting, Dennis, Schüle, Birgitt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275022/
https://www.ncbi.nlm.nih.gov/pubmed/25566351
http://dx.doi.org/10.12688/f1000research.3281.2