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Statins inhibit insulin-like growth factor action in first trimester placenta by altering insulin-like growth factor 1 receptor glycosylation

The rapid rise in obesity, metabolic syndrome and type 2 diabetes is one of the major healthcare problems of the Western world. Affected individuals are often treated with statins (3-hydroxy-3-methylglutaryl co-enzyme A [HMG CoA] reductase inhibitors) to reduce circulating cholesterol levels and the...

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Detalles Bibliográficos
Autores principales: Forbes, Karen, Shah, Vinit K., Siddals, Kirk, Gibson, J. Martin, Aplin, John D., Westwood, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275043/
https://www.ncbi.nlm.nih.gov/pubmed/25304981
http://dx.doi.org/10.1093/molehr/gau093

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