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Matching the Decay Half-Life with the Biological Half-Life: ImmunoPET Imaging with (44)Sc-Labeled Cetuximab Fab Fragment

[Image: see text] Scandium-44 (t(1/2) = 3.9 h) is a relatively new radioisotope of potential interest for use in clinical positron emission tomography (PET). Herein, we report, for the first time, the room-temperature radiolabeling of proteins with (44)Sc for in vivo PET imaging. For this purpose, t...

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Detalles Bibliográficos
Autores principales: Chakravarty, Rubel, Goel, Shreya, Valdovinos, Hector F., Hernandez, Reinier, Hong, Hao, Nickles, Robert J., Cai, Weibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275156/
https://www.ncbi.nlm.nih.gov/pubmed/25389697
http://dx.doi.org/10.1021/bc500415x