Cargando…

Folate Receptor-Mediated Enhanced and Specific Delivery of Far-Red Light-Activatable Prodrugs of Combretastatin A-4 to FR-Positive Tumor

[Image: see text] We examined the concept of a novel prodrug strategy in which anticancer drug can be locally released by visible/near IR light, taking advantage of the photodynamic process and photo-unclick chemistry. Our most recently formulated prodrug of combretastatin A-4, Pc-(L-CA4)(2), showed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nkepang, Gregory, Bio, Moses, Rajaputra, Pallavi, Awuah, Samuel G., You, Youngjae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275160/ https://www.ncbi.nlm.nih.gov/pubmed/25351441 http://dx.doi.org/10.1021/bc500376j

Ejemplares similares

Far-Red Light Activatable, Multifunctional Prodrug for Fluorescence Optical Imaging and Combinational Treatment
por: Bio, Moses, et al.
Publicado: (2014)

Folate-PEG Conjugates of a Far-Red Light-Activatable Paclitaxel Prodrug to Improve Selectivity toward Folate Receptor-Positive Cancer Cells
por: Thapa, Pritam, et al.
Publicado: (2017)

A generator of peroxynitrite activatable with red light
por: Parisi, Cristina, et al.
Publicado: (2021)

Red-Light-Activatable AND-Gated Antitumor Immunosuppressant
por: Zhou, Ziqi, et al.
Publicado: (2023)

In vivo and in vitro evaluation of combretastatin A-4 and its sodium phosphate prodrug
por: Grosios, K, et al.
Publicado: (1999)

An ultrasound-activatable platinum prodrug for sono-sensitized chemotherapy
por: Liu, Gongyuan, et al.
Publicado: (2023)

Oral liposomal delivery of an activatable budesonide prodrug reduces colitis in experimental mice
por: Xian, Shiyun, et al.
Publicado: (2023)

Excited‐State Dynamics of a Two‐Photon‐Activatable Ruthenium Prodrug
por: Greenough, Simon E., et al.
Publicado: (2016)

Molecular Processes of Dodder Haustorium Formation on Host Plant under Low Red/Far Red (R/FR) Irradiation
por: Pan, Hangkai, et al.
Publicado: (2022)

Magnetic resonance imaging and spectroscopy of combretastatin A(4) prodrug-induced disruption of tumour perfusion and energetic status
Publicado: (1998)

Magnetic resonance imaging and spectroscopy of combretastatin A4 prodrug-induced disruption of tumour perfusion and energetic status.
por: Beauregard, D. A., et al.
Publicado: (1998)

Development Of Novel Liposome-Encapsulated Combretastatin A4 Acylated Derivatives: Prodrug Approach For Improving Antitumor Efficacy
por: Gu, Yongwei, et al.
Publicado: (2019)

9‐Cyano‐10‐telluriumpyronin Derivatives as Red‐light‐activatable Raman Probes
por: Kawatani, Minoru, et al.
Publicado: (2022)

Establishment and characterization of stable red, far-red (fR) and near infra-red (NIR) transfected canine prostate cancer cell lines
por: Liu, Wen, et al.
Publicado: (2020)

Novel far-red-emitting SrGdAlO(4):Mn(4+) phosphors with excellent responsiveness to phytochrome P(FR) for plant growth lighting
por: Sun, Qi, et al.
Publicado: (2018)

Conditionally Activatable Visible-Light Photocages
por: Bojtár, Márton, et al.
Publicado: (2020)

The effect of red light and far-red light conditions on secondary metabolism in Agarwood
por: Kuo, Tony Chien-Yen, et al.
Publicado: (2015)

Hydrogen peroxide-activatable antioxidant prodrug as a targeted therapeutic agent for ischemia-reperfusion injury
por: Lee, Dongwon, et al.
Publicado: (2015)

Dual-channel NIR activatable theranostic prodrug for in vivo spatiotemporal tracking thiol-triggered chemotherapy
por: Ye, Mingzhou, et al.
Publicado: (2016)

An esterase-activatable prodrug formulated liposome strategy: potentiating the anticancer therapeutic efficacy and drug safety
por: Shi, Linlin, et al.
Publicado: (2021)

Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance
por: Farran, Batoul, et al.
Publicado: (2019)

Cathepsin B-Overexpressed Tumor Cell Activatable Albumin-Binding Doxorubicin Prodrug for Cancer-Targeted Therapy
por: Cho, Hanhee, et al.
Publicado: (2021)

Neutrophil Elastase-Activatable Prodrugs Based on an Alkoxyamine Platform to Deliver Alkyl Radicals Cytotoxic to Tumor Cells
por: Seren, Seda, et al.
Publicado: (2022)

Tumor-specific activatable biopolymer nanoparticles stabilized by hydroxyethyl starch prodrug for self-amplified cooperative cancer therapy
por: Xiong, Yuxuan, et al.
Publicado: (2022)

EARLY STAGES IN THE DEVELOPMENT OF PLASTID FINE STRUCTURE IN RED AND FAR-RED LIGHT
por: Klein, Shimon, et al.
Publicado: (1964)

Identification of folate receptor α (FRα) binding oligopeptides and their evaluation for targeted virotherapy applications
por: Hulin-Curtis, Sarah L., et al.
Publicado: (2020)

Photobodies: Light‐Activatable Single‐Domain Antibody Fragments
por: Jedlitzke, Benedikt, et al.
Publicado: (2019)

Cytotoxicity Studies of Novel Combretastatin and Pterostilbene Derivatives
por: Jakubowska, Joanna, et al.
Publicado: (2014)

Combretastatin-Inspired Heterocycles as Antitubulin Anticancer Agents
por: Hura, Neha, et al.
Publicado: (2018)

Novel Selective Estrogen Receptor Ligand Conjugates Incorporating Endoxifen-Combretastatin and Cyclofenil-Combretastatin Hybrid Scaffolds: Synthesis and Biochemical Evaluation
por: Kelly, Patrick M., et al.
Publicado: (2017)

Erythrocytic bioactivation of nitrite and its potentiation by far-red light
por: Wajih, Nadeem, et al.
Publicado: (2018)

Far-Red Light Acclimation for Improved Mass Cultivation of Cyanobacteria
por: Silkina, Alla, et al.
Publicado: (2019)

Long‐term adaptation of Arabidopsis thaliana to far‐red light
por: Hu, Chen, et al.
Publicado: (2021)

Molecular Evolution of Far-Red Light-Acclimated Photosystem II
por: Gisriel, Christopher J., et al.
Publicado: (2022)

The Electronic Origin of Far‐Red‐Light‐Driven Oxygenic Photosynthesis
por: Sirohiwal, Abhishek, et al.
Publicado: (2022)

A red and far-red light receptor mutation confers resistance to the herbicide glyphosate
por: Sharkhuu, Altanbadralt, et al.
Publicado: (2014)

Red/far-red light signals regulate the activity of the carbon-concentrating mechanism in cyanobacteria
por: Oren, Nadav, et al.
Publicado: (2021)

Use of red, far-red, and near-infrared light in imaging of yeasts and filamentous fungi
por: Pócsi, István, et al.
Publicado: (2022)

Galactose Modified Liposomes for Effective Co-Delivery of Doxorubicin and Combretastatin A4
por: Lian, Bo, et al.
Publicado: (2021)

The role of folate receptor alpha (FRα) in the response of malignant pleural mesothelioma to pemetrexed-containing chemotherapy
por: Nutt, J E, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_deum6c7isha5e43oie2ikqrg5r