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Simple Radiometric Method for Accurately Quantitating Epitope Densities of Hapten–Protein Conjugates with Sulfhydryl Linkages

[Image: see text] Control of small molecule hapten epitope densities on antigenic carrier proteins is essential for development and testing of optimal conditions for vaccines. Yet, accurate determination of epitope density can be extremely difficult to accomplish, especially with the use of small ha...

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Detalles Bibliográficos
Autores principales: Peterson, Eric C., Hambuchen, Michael D., Tawney, Rachel L., Gunnell, Melinda G., Cowell, James L., Lay, Jackson O., Blough, Bruce E., Carroll, F. Ivy, Owens, S. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275166/
https://www.ncbi.nlm.nih.gov/pubmed/25426820
http://dx.doi.org/10.1021/bc500456z