Cargando…

Interleukin-34 Restores Blood–Brain Barrier Integrity by Upregulating Tight Junction Proteins in Endothelial Cells

Interleukin-34 (IL-34) is a newly discovered cytokine as an additional ligand for colony stimulating factor-1 receptor (CSF1R), and its functions are expected to overlap with colony stimulating factor-1/macrophage-colony stimulating factor. We have previously shown that the IL-34 is primarily produc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jin, Shijie, Sonobe, Yoshifumi, Kawanokuchi, Jun, Horiuchi, Hiroshi, Cheng, Yi, Wang, Yue, Mizuno, Tetsuya, Takeuchi, Hideyuki, Suzumura, Akio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275171/ https://www.ncbi.nlm.nih.gov/pubmed/25535736 http://dx.doi.org/10.1371/journal.pone.0115981

Ejemplares similares

Interleukin-1β Induces Blood–Brain Barrier Disruption by Downregulating Sonic Hedgehog in Astrocytes
por: Wang, Yue, et al.
Publicado: (2014)

GM-CSF increases LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia
por: Parajuli, Bijay, et al.
Publicado: (2012)

Fingolimod Phosphate Attenuates Oligomeric Amyloid β–Induced Neurotoxicity via Increased Brain-Derived Neurotrophic Factor Expression in Neurons
por: Doi, Yukiko, et al.
Publicado: (2013)

Granulocyte-Colony Stimulating Factor Attenuates Oligomeric Amyloid β Neurotoxicity by Activation of Neprilysin
por: Doi, Yukiko, et al.
Publicado: (2014)

FGF-2 released from degenerating neurons exerts microglial-induced neuroprotection via FGFR3-ERK signaling pathway
por: Noda, Mariko, et al.
Publicado: (2014)

The neuroprotective effects of milk fat globule-EGF factor 8 against oligomeric amyloid β toxicity
por: Li, Endong, et al.
Publicado: (2012)

Blockade of Gap Junction Hemichannel Suppresses Disease Progression in Mouse Models of Amyotrophic Lateral Sclerosis and Alzheimer's Disease
por: Takeuchi, Hideyuki, et al.
Publicado: (2011)

Interleukin-19 Acts as a Negative Autocrine Regulator of Activated Microglia
por: Horiuchi, Hiroshi, et al.
Publicado: (2015)

Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation
por: Watanabe, Mitsuru, et al.
Publicado: (2016)

Gap junctions and hemichannels composed of connexins: potential therapeutic targets for neurodegenerative diseases
por: Takeuchi, Hideyuki, et al.
Publicado: (2014)

Interleukin-19 Abrogates Experimental Autoimmune Encephalomyelitis by Attenuating Antigen-Presenting Cell Activation
por: Horiuchi, Hiroshi, et al.
Publicado: (2021)

Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer's disease
por: Parajuli, B, et al.
Publicado: (2013)

Breaking through the tight junction barrier
Publicado: (1993)

Tight junctions and the modulation of barrier function in disease
por: Förster, Carola
Publicado: (2008)

Tight Junctions of the Outer Blood Retina Barrier
por: Naylor, Aisling, et al.
Publicado: (2019)

Brain barriers: Crosstalk between complex tight junctions and adherens junctions
por: Tietz, Silvia, et al.
Publicado: (2015)

Endothelial tight junctions form the blood–brain barrier
por: Bonetta, Laura
Publicado: (2005)

Bile duct epithelial tight junctions and barrier function
por: Rao, R.K., et al.
Publicado: (2013)

Regulation of the intestinal barrier by nutrients: The role of tight junctions
por: Suzuki, Takuya
Publicado: (2020)

Trans-Compartmental Regulation of Tight Junction Barrier Function
por: Naser, Amna N., et al.
Publicado: (2022)

GAPDH Released from Lactobacillus johnsonii MG Enhances Barrier Function by Upregulating Genes Associated with Tight Junctions
por: Lyu, Mengying, et al.
Publicado: (2023)

Cellular and molecular mechanism of interleukin-1β modulation of Caco-2 intestinal epithelial tight junction barrier
por: Al-Sadi, Rana, et al.
Publicado: (2011)

O-GlcNAcylation Inhibition Upregulates Connexin43 Expression in the Endothelium to Protect the Tight Junction Barrier in Diabetic Retinopathy
por: Liu, Guodong, et al.
Publicado: (2023)

Tight Junctions: A Barrier to the Initiation and Progression of Breast Cancer?
por: Brennan, Kieran, et al.
Publicado: (2010)

PLEKHA7 modulates epithelial tight junction barrier function
por: Paschoud, Serge, et al.
Publicado: (2014)

Enteropathogenic E. coli: breaking the intestinal tight junction barrier
por: Singh, Anand Prakash, et al.
Publicado: (2016)

“You Shall Not Pass”—tight junctions of the blood brain barrier
por: Bauer, Hans-Christian, et al.
Publicado: (2014)

Urothelial Tight Junction Barrier Dysfunction Sensitizes Bladder Afferents
por: Montalbetti, Nicolas, et al.
Publicado: (2017)

Structural dynamics of tight junctions modulate the properties of the epithelial barrier
por: Tervonen, Aapo, et al.
Publicado: (2019)

Computational Nanoscopy of Tight Junctions at the Blood–Brain Barrier Interface
por: Rajagopal, Nandhini, et al.
Publicado: (2019)

IL-1β and the Intestinal Epithelial Tight Junction Barrier
por: Kaminsky, Lauren W., et al.
Publicado: (2021)

Nano-scale architecture of blood-brain barrier tight-junctions
por: Sasson, Esther, et al.
Publicado: (2021)

Keratin 76 Is Required for Tight Junction Function and Maintenance of the Skin Barrier
por: DiTommaso, Tia, et al.
Publicado: (2014)

Opening Tight Junctions may be Key to Opening the Blood–Prostate Barrier
por: Shang, Yonggang, et al.
Publicado: (2014)

Trends in drug delivery through tissue barriers containing tight junctions
por: Tscheik, Christian, et al.
Publicado: (2013)

Tight Junction barriers in human hair follicles – role of claudin-1
por: Zorn-Kruppa, Michaela, et al.
Publicado: (2018)

Layered defense: how mucus and tight junctions seal the intestinal barrier
por: Capaldo, Christopher T., et al.
Publicado: (2017)

Are claudin-5 tight-junction proteins in the blood-brain barrier porous?
por: Fisher, David, et al.
Publicado: (2020)

Claudin-12 is not required for blood–brain barrier tight junction function
por: Castro Dias, Mariana, et al.
Publicado: (2019)

Effects of mucopolysaccharide polysulphate on tight junction barrier in human epidermal keratinocytes
por: Fujikawa, Mika, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qscjdvmjrb7birrlm4pf0demv6